Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications

P Tan, H Fu, X Ma - Nano Today, 2021 - Elsevier
Antibiotic resistance caused by antibiotic abuse, especially the emergence of multi-drug
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …

Gathering brings strength: How organic aggregates boost disease phototheranostics

J Qi, H Ou, Q Liu, D Ding - Aggregate, 2021 - Wiley Online Library
Phototheranostics that concurrently and complementarily integrate real‐time diagnosis and
in situ therapeutic capabilities in one platform has become the advancing edge of precision …

Supramolecular assembled programmable nanomedicine as in situ cancer vaccine for cancer immunotherapy

Y Zhang, S Ma, X Liu, Y Xu, J Zhao, X Si… - Advanced …, 2021 - Wiley Online Library
Using nanotechnology for improving the immunotherapy efficiency represents a major
research interest in recent years. However, there are paradoxes and obstacles in using a …

Synthesizing biomaterials in living organisms

X Zhang, J Wang, Y Zhang, Z Yang, J Gao… - Chemical Society …, 2023 - pubs.rsc.org
Living organisms fabricate biomacromolecules such as DNA, RNA, and proteins by the self-
assembly process. The research on the mechanism of biomacromolecule formation also …

A comprehensive review on peptide-bearing biomaterials: From ex situ to in situ self-assembly

SY Qin, JQ Feng, YJ Cheng, WL Liu, AQ Zhang… - Coordination Chemistry …, 2024 - Elsevier
In the last few decades, we have witnessed the great advances of molecular self-assembly
in biomedical applications. Among the building blocks for molecular self-assembly, peptide …

Intelligent biomaterialomics: molecular design, manufacturing, and biomedical applications

Y Yi, HW An, H Wang - Advanced Materials, 2024 - Wiley Online Library
Materialomics integrates experiment, theory, and computation in a high‐throughput manner,
and has changed the paradigm for the research and development of new functional …

Transformable ECM deprivation system effectively suppresses renal cell carcinoma by reversing anoikis resistance and increasing chemotherapy sensitivity

L Wang, C Li, J Wang, G Yang, Y Lv, B Fu… - Advanced …, 2022 - Wiley Online Library
Extracellular matrix (ECM) is crucial in various biological functions during tumor progression,
including induction of anoikis resistance and cell adhesion‐mediated drug resistance (CAM …

Intracellular self-assembly of peptides to induce apoptosis against drug-resistant melanoma

M Sun, C Wang, M Lv, Z Fan, J Du - Journal of the American …, 2022 - ACS Publications
Biosynthesis has been a diverse toolbox to develop bioactive molecules and materials,
especially for fabricating modified peptides and their assemblies induced by enzymes …

Noncanonical amino acids for hypoxia-responsive peptide self-assembly and fluorescence

B Hu, N Song, Y Cao, M Li, X Liu, Z Zhou… - Journal of the …, 2021 - ACS Publications
Design of endogenous stimuli-responsive amino acids allows for precisely modulating
proteins or peptides under a biological microenvironment and thereby regulating their …

Self-assembled peptide drug delivery systems

J Yang, HW An, H Wang - ACS Applied Bio Materials, 2020 - ACS Publications
Over the past several decades, rapid advances have been made in the application of
nanomaterials in the biomedical field including bioimaging and drug delivery. Owing to the …