A review of the antioxidant mechanisms of polyphenol compounds related to iron binding

NR Perron, JL Brumaghim - Cell biochemistry and biophysics, 2009 - Springer
In this review, primary attention is given to the antioxidant (and prooxidant) activity of
polyphenols arising from their interactions with iron both in vitro and in vivo. In addition, an …

Development of Methods for the Determination of pKa Values

J Reijenga, A Van Hoof, A Van Loon… - Analytical chemistry …, 2013 - journals.sagepub.com
The acid dissociation constant (pKa) is among the most frequently used physicochemical
parameters, and its determination is of interest to a wide range of research fields. We …

Determination of pKa values of active pharmaceutical ingredients

S Babić, AJM Horvat, DM Pavlović… - TrAC Trends in …, 2007 - Elsevier
The acid dissociation constant is an important physicochemical parameter of a substance,
and knowledge of it is of fundamental importance in a wide range of applications and …

In situ synthesis of metal nanoparticles and selective naked-eye detection of lead ions from aqueous media

K Yoosaf, BI Ipe, CH Suresh… - The Journal of Physical …, 2007 - ACS Publications
A novel one step synthesis of water soluble Au and Ag nanoparticles has been reported at
room temperature using a naturally occurring bifunctional molecule, namely, gallic acid. The …

KEV: A free software for calculating the equilibrium composition and determining the equilibrium constants using UV–Vis and potentiometric data

AN Meshkov, GA Gamov - Talanta, 2019 - Elsevier
Present paper reports on an algorithm for calculating the equilibrium composition of several
compounds mixture if their total (equilibrium) concentrations and the equilibrium constants of …

Determination of pKa values of some hydroxylated benzoic acids in methanol–water binary mixtures by LC methodology and potentiometry

FZ Erdemgil, S Şanli, N Şanli, G Özkan, J Barbosa… - Talanta, 2007 - Elsevier
An accurate estimation of pKa values in methanol–water binary mixtures is very important for
several separation techniques such as liquid chromatography and capillary electrophoresis …

[HTML][HTML] Dermal drug delivery of phytochemicals with phenolic structure via lipid-based nanotechnologies

V Gugleva, N Ivanova, Y Sotirova, V Andonova - Pharmaceuticals, 2021 - mdpi.com
Phenolic compounds are a large, heterogeneous group of secondary metabolites found in
various plants and herbal substances. From the perspective of dermatology, the most …

Sinapic acid co-amorphous systems with amino acids for improved solubility and antioxidant activity

E Garbiec, N Rosiak, E Tykarska, P Zalewski… - International Journal of …, 2023 - mdpi.com
The objective of this study was to obtain co-amorphous systems of poorly soluble sinapic
acid using amino acids as co-formers. In order to assess the probability of the interaction of …

[HTML][HTML] Glycerol as Alternative Co-Solvent for Water Extraction of Polyphenols from Carménère Pomace: Hot Pressurized Liquid Extraction and Computational …

NL Huamán-Castilla, MS Mariotti-Celis… - Biomolecules, 2020 - mdpi.com
Glycerol is a co-solvent for water extraction that has been shown to be highly effective for
obtaining polyphenol extracts under atmospheric conditions. However, its efficacy under …

Predicting how polyphenol antioxidants prevent DNA damage by binding to iron

NR Perron, JN Hodges, M Jenkins… - Inorganic …, 2008 - ACS Publications
Prevention of oxidative DNA damage due to hydroxyl radical is important for the prevention
and treatment of disease. Because of their widely recognized antioxidant ability, 12 …