The gastrointestinal tract of humans is a complex microbial ecosystem known as gut
microbiota. The microbiota is involved in several critical physiological processes such as …

The circadian clock regulates daily rhythms of numerous physiological activities through
tightly coordinated modulation of gene expression and biochemical functions. Circadian …

The immune system protects the body from infectious agents such as bacteria, viruses, or
fungi. Once encountered with pathogens or antigens, the innate and adaptive arms of the …

Cancer is one of the leading causes of death globally. The development of drug resistance
is the main contributor to cancer-related mortality. Cancer cells exploit multiple mechanisms …

Combined chemotherapy is a treatment method based on the simultaneous use of two or
more therapeutic agents; it is frequently necessary to produce a more effective treatment for …

Tumor-associated macrophages (TAMs) play a pivotal role in the progression and
resistance of tumors to different anticancer drugs. TAMs can modulate the tumor …

Circadian timekee** mechanisms and cell cycle regulation share thematic biological
principles in responding to signals, repairing cellular damage, coordinating metabolism, and …

Melatonin, the 'hormone of darkness' is a neuronal hormone secreted by the pineal gland
and other extra pineal sites. Responsible for the circadian rhythm and seasonal behaviour of …

Melatonin is a serotonin-derived pineal gland hormone with many biological functions like
regulating the sleep-wake cycle, circadian rhythm, menstrual cycle, aging, immunity, and …

Melatonin possesses the indoleamine structure and exerts antioxidant and anti-inflammatory
actions and other physiological properties. Physical exercise can influence secretion of …