Machine learning for clinical decision support in infectious diseases: a narrative review of current applications

N Peiffer-Smadja, TM Rawson, R Ahmad… - Clinical Microbiology …, 2020 - Elsevier
Background Machine learning (ML) is a growing field in medicine. This narrative review
describes the current body of literature on ML for clinical decision support in infectious …

Artificial intelligence and machine learning assisted drug delivery for effective treatment of infectious diseases

S He, LG Leanse, Y Feng - Advanced drug delivery reviews, 2021 - Elsevier
In the era of antimicrobial resistance, the prevalence of multidrug-resistant microorganisms
that resist conventional antibiotic treatment has steadily increased. Thus, it is now …

Beyond sparsity: Tree regularization of deep models for interpretability

M Wu, M Hughes, S Parbhoo, M Zazzi, V Roth… - Proceedings of the …, 2018 - ojs.aaai.org
The lack of interpretability remains a key barrier to the adoption of deep models in many
applications. In this work, we explicitly regularize deep models so human users might step …

The Health Gym: synthetic health-related datasets for the development of reinforcement learning algorithms

NIH Kuo, MN Polizzotto, S Finfer, F Garcia… - Scientific data, 2022 - nature.com
In recent years, the machine learning research community has benefited tremendously from
the availability of openly accessible benchmark datasets. Clinical data are usually not …

[HTML][HTML] Combining kernel and model based learning for HIV therapy selection

S Parbhoo, J Bogojeska, M Zazzi, V Roth… - AMIA Summits on …, 2017 - ncbi.nlm.nih.gov
We present a mixture-of-experts approach for HIV therapy selection. The heterogeneity in
patient data makes it difficult for one particular model to succeed at providing suitable …

Navigating the Landscape: A Comprehensive Review of Current Virus Databases

M Ritsch, NA Cassman, S Saghaei, M Marz - Viruses, 2023 - mdpi.com
Viruses are abundant and diverse entities that have important roles in public health,
ecology, and agriculture. The identification and surveillance of viruses rely on an …

[HTML][HTML] Generating synthetic clinical data that capture class imbalanced distributions with generative adversarial networks: Example using antiretroviral therapy for …

I Nicholas, H Kuo, F Garcia, A Sönnerborg… - Journal of Biomedical …, 2023 - Elsevier
Objective: Clinical data's confidential nature often limits the development of machine
learning models in healthcare. Generative adversarial networks (GANs) can synthesise …

Determinants of HIV-1 late presentation in patients followed in Europe

MNS Miranda, M **arilho, V Pimentel, MRO Martins… - Pathogens, 2021 - mdpi.com
To control the Human Immunodeficiency Virus (HIV) pandemic, the World Health
Organization (WHO) set the 90-90-90 target to be reached by 2020. One major threat to …

A survey of machine learning applications in HIV clinical research and care

KR Bisaso, GT Anguzu, SA Karungi, A Kiragga… - Computers in biology …, 2017 - Elsevier
A wealth of genetic, demographic, clinical and biomarker data is collected from routine
clinical care of HIV patients and exists in the form of medical records available among the …

Unraveling the web of viroinformatics: computational tools and databases in virus research

D Sharma, P Priyadarshini, S Vrati - Journal of virology, 2015 - Am Soc Microbiol
The beginning of the second century of research in the field of virology (the first virus was
discovered in 1898) was marked by its amalgamation with bioinformatics, resulting in the …