Preeclampsia and cardiovascular risk for offspring

W Wojczakowski, Ż Kimber-Trojnar, F Dziwisz… - Journal of Clinical …, 2021 - mdpi.com
There is growing evidence of long-term cardiovascular sequelae in children after in utero
exposure to preeclampsia. Maternal hypertension and/or placental ischaemia during …

Lasting effects of intrauterine exposure to preeclampsia on offspring and the underlying mechanism

HQ Lu, R Hu - American journal of perinatology reports, 2019 - thieme-connect.com
Preeclampsia is a common pregnancy complication which can have adverse impact on both
mother and baby. In addition to the short term effects, a large body of epidemiological …

Prenatal androgen exposure causes hypertension and gut microbiota dysbiosis

SB Sherman, N Sarsour, M Salehi, A Schroering… - Gut …, 2018 - Taylor & Francis
Background: Conditions of excess androgen in women, such as polycystic ovary syndrome
(PCOS), often exhibit intergenerational transmission. One way in which the risk for PCOS …

The cardiovascular subtleties of testosterone on gender-affirming hormone therapy

JD Santos, JT Oliveira-Neto… - American Journal of …, 2023 - journals.physiology.org
The growing number of people who identify themselves as transgender has gained
increased attention in recent years and will certainly impact personalized clinical practices …

Pregnancy upregulates angiotensin type 2 receptor expression and increases blood flow in uterine arteries of rats

JS Mishra, K Gopalakrishnan, S Kumar - Biology of reproduction, 2018 - academic.oup.com
Normal pregnancy is associated with decreased uterine vascular contraction and increased
blood flow even though angiotensin II (AngII) levels are increased. AngII not only activates …

Cardiovascular disease risk in offspring of polycystic ovary syndrome

NM Shawky - Frontiers in Endocrinology, 2022 - frontiersin.org
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting women
at reproductive age. PCOS diagnosis (Rotterdam criteria) is based on the presence of two …

[HTML][HTML] Abnormal CYP11A1 gene expression induces excessive autophagy, contributing to the pathogenesis of preeclampsia

T Pan, G He, M Chen, C Bao, Y Chen, G Liu, M Zhou… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abnormal CYP11A1 gene expression induces excessive autophagy, contributing to the
pathogenesis of preeclampsia - PMC Back to Top Skip to main content NIH NLM Logo Access …

Sex-specific metabolic outcomes in offspring of female rats born small or exposed to stress during pregnancy

JN Cheong, JSM Cuffe, AJ Jefferies, K Anevska… - …, 2016 - academic.oup.com
Low birth weight increases adult metabolic disease risk in both the first (F1) and second (F2)
generation. Physiological stress during pregnancy in F1 females that were born small …

Selective deletion of endothelial mineralocorticoid receptor protects from vascular dysfunction in sodium-restricted female mice

JL Faulkner, E Lluch, S Kennard, G Antonova… - Biology of sex …, 2020 - Springer
Background Recent evidence by our laboratory demonstrates that women and female mice
endogenously express higher endothelial mineralocorticoid receptor (ECMR) than males …

Affinity ultrafiltration and UPLC-HR-Orbitrap-MS based screening of thrombin-targeted small molecules with anticoagulation activity from Poecilobdella manillensis

Q Huang, J Tang, X Chai, W Ren, JB Wang… - … of Chromatography B, 2021 - Elsevier
This study aims to screen potential anticoagulant components from leeches, a
representative animal-sourced traditional Chinese medicine using thrombin (THR)-targeted …