Targeting triple negative breast cancer stem cells using nanocarriers

N Dasari, GS Guntuku, SKSS Pindiprolu - Discover Nano, 2024 - Springer
Breast cancer is a complex and heterogeneous disease, encompassing various subtypes
characterized by distinct molecular features, clinical behaviors, and treatment responses …

Dynamic interplay of nuclear receptors in tumor cell plasticity and drug resistance: shifting gears in Malignant transformations and applications in cancer therapeutics

B BharathwajChetty, A Sajeev, R Vishwa… - Cancer and Metastasis …, 2024 - Springer
Recent advances have brought forth the complex interplay between tumor cell plasticity and
its consequential impact on drug resistance and tumor recurrence, both of which are critical …

Estrogen-related receptor alpha (ERRα) promotes the migration, invasion and angiogenesis of breast cancer stem cell-like cells

K Muduli, J Pradhan, M Prusty, AP Samal, KS Reddy… - Medical Oncology, 2024 - Springer
Breast cancer progression, metastasis and recurrence are largely driven by breast cancer
stem cells (BCSCs), which constitute a subset of tumor cells exhibiting stem cell …

Plasmodium falciparum J‐dot localized J domain protein A8iJp modulates the chaperone activity of human HSPA8

W Sahu, T Bai, A Das, S Mukherjee, A Prusty… - FEBS …, 2024 - Wiley Online Library
Plasmodium falciparum renovates the host erythrocyte to survive during intraerythrocytic
development. This renovation requires many parasite proteins to unfold and move outside …

[HTML][HTML] PPARα-ERRα crosstalk mitigates metabolic dysfunction-associated steatotic liver disease progression

MB Antwi, S Lefere, D Clarisse, L Koorneef, A Heldens… - Metabolism, 2025 - Elsevier
Background and aims Metabolic dysfunction-associated steatotic liver disease (MASLD), the
most prevalent liver disease worldwide, continues to rise. More effective therapeutic …

A study with cancer stem cells and three-dimensional tumoroids: investigation of the combined effects of 5-fluorouracil and doxorubicin in breast cancer

S Erden Tayhan - Medical Oncology, 2024 - Springer
The purpose of the present study was in vitro determination of the combined effects of
doxorubucin and 5-fluorouracil by 2D and 3D culture conditions on breast cancer using MCF …

[HTML][HTML] Impact of de novo cholesterol biosynthesis on the initiation and progression of breast cancer

D Coradini - Biomolecules, 2024 - mdpi.com
Cholesterol (CHOL) is a multifaceted lipid molecule. It is an essential structural component
of cell membranes, where it cooperates in regulating the intracellular trafficking and …

Optimisation of Levilactobacillus brevis-fermented finger millet (Eleusine coracana) and evaluation of its effects on cancer cells (HCT116 and MDA-MB-231)

SK Mahanta, PP Nayak, K Muduli, S Elangovan… - Methods, 2024 - Elsevier
The objective of this study was to optimise the millet formulation using Levilactobacillus
brevis and to evaluate its anticarcinogenic potential in vitro. The formula was developed in …

[PDF][PDF] Discover Nano

N Dasari, GS Guntuku, SKSS Pindiprolu - 2024 - d-nb.info
Breast cancer is a complex and heterogeneous disease, encompassing various subtypes
characterized by distinct molecular features, clinical behaviors, and treatment responses …

Vaccine-induced T-helper-1 and endocrine therapy in an estrogen receptor alpha low breast cancer model

DL Cecil, E Gad, L Corulli, K Potts… - Medical Research Archives, 2024 - esmed.org
The standard of care options for patients with triple negative breast cancer is limited to
primarily surgery and chemotherapy. Recent evidence has demonstrated that combining …