One hundred years have passed since Warburg discovered alterations in cancer
metabolism, more than 70 years since Sidney Farber introduced anti-folates that …

Lactate dehydrogenase (LDH) is a terminating enzyme in the metabolic pathway of
anaerobic glycolysis with end product of lactate from glucose. The lactate formation is crucial …

Cancer cell metabolism including aerobic glycolysis, amino acid and fatty acid metabolism,
has been extensively studied. Metabolic reprogramming is a major hallmark of cancer …

Inhibitors of the lipogenic enzyme fatty acid synthase (FASN) have attracted much attention
in the last decade as potential targeted cancer therapies. However, little is known about the …

Metastasis is the predominant reason for high mortality of hepatocellular carcinoma (HCC)
patients. It is critical to explore the molecular mechanism underlying HCC metastasis. Here …

This review article delves into the complexities of granuloma formation, focusing on the
metabolic reprogramming within these immune structures, especially in tuberculosis and …

Cancer metabolism is how cancer cells utilize nutrients and energy to support their growth
and proliferation. Unlike normal cells, cancer cells have a unique metabolic profile that …

Ovarian cancer is a leading cause of death among gynecologic tumors, often detected at
advanced stages. Metabolic reprogramming and increased lipid biosynthesis are key factors …

Aberrant lipid metabolism provides bioenergetic, biosynthetic, and redox supplies to cancer
cells. Previous studies have reported differential lipid profiling in thyroid malignancies. Sterol …

ABSTRACT Introduction Brain metastasis (BrM) is a key contributor to morbidity and
mortality in breast cancer patients, especially among high-risk epidermal growth factor …