Concepts of extracellular matrix remodelling in tumour progression and metastasis

J Winkler, A Abisoye-Ogunniyan, KJ Metcalf… - Nature …, 2020 - nature.com
Tissues are dynamically shaped by bidirectional communication between resident cells and
the extracellular matrix (ECM) through cell-matrix interactions and ECM remodelling …

Neutrophil intrinsic and extrinsic regulation of NETosis in health and disease

V Poli, I Zanoni - Trends in microbiology, 2023 - cell.com
Neutrophil extracellular traps (NETs) evolved to protect the host against microbial infections
and are formed by a web-like structure of DNA that is decorated with antimicrobial effectors …

Targeting potential drivers of COVID-19: Neutrophil extracellular traps

BJ Barnes, JM Adrover, A Baxter-Stoltzfus… - Journal of Experimental …, 2020 - rupress.org
Disclosures: MR Looney reported" other" from Neutrolis outside the submitted work. RE
Schwartz is a Sponsored Advisory Board Member for Miromatrix Inc. JD Spicer reported …

Excessive neutrophils and neutrophil extracellular traps in COVID-19

J Wang, Q Li, Y Yin, Y Zhang, Y Cao, X Lin… - Frontiers in …, 2020 - frontiersin.org
Background: Cases of excessive neutrophil counts in the blood in severe coronavirus
disease (COVID-19) patients have drawn significant attention. Neutrophil infiltration was …

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients

AC Aschenbrenner, M Mouktaroudi, B Krämer… - Genome medicine, 2021 - Springer
Abstract Background The SARS-CoV-2 pandemic is currently leading to increasing numbers
of COVID-19 patients all over the world. Clinical presentations range from asymptomatic …

Neutrophil extracellular traps in immunity and disease

V Papayannopoulos - Nature Reviews Immunology, 2018 - nature.com
Neutrophils are innate immune phagocytes that have a central role in immune defence. Our
understanding of the role of neutrophils in pathogen clearance, immune regulation and …

Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy

F Binet, G Cagnone, S Crespo-Garcia, M Hata… - Science, 2020 - science.org
INTRODUCTION Vision provides a critical survival advantage but requires a tight coupling
between neuronal energy demands and their vascular supply. The degeneration and …

The role of neutrophil extracellular traps in acute lung injury

D Scozzi, F Liao, AS Krupnick, D Kreisel… - Frontiers in …, 2022 - frontiersin.org
Acute lung injury (ALI) is a heterogeneous inflammatory condition associated with high
morbidity and mortality. Neutrophils play a key role in the development of different forms of …

Molecular and cellular mechanisms of cardiovascular disorders in diabetes

MS Shah, M Brownlee - Circulation research, 2016 - Am Heart Assoc
The clinical correlations linking diabetes mellitus with accelerated atherosclerosis,
cardiomyopathy, and increased post-myocardial infarction fatality rates are increasingly …

Neutrophils in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus: same foe different MO

M Fresneda Alarcon, Z McLaren, HL Wright - Frontiers in immunology, 2021 - frontiersin.org
Dysregulated neutrophil activation contributes to the pathogenesis of autoimmune diseases
including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Neutrophil …