Advances in pyranopyrazole scaffolds' syntheses using sustainable catalysts—a review

RK Ganta, N Kerru, S Maddila, SB Jonnalagadda - Molecules, 2021 - mdpi.com
Heterogeneous catalysis plays a crucial role in many chemical processes, including
advanced organic preparations and the design and synthesis of new organic moieties …

Recent progress of bioactivities, mechanisms of action, total synthesis, structural modifications and structure-activity relationships of indole derivatives: a review

T Li, H Xu - Mini Reviews in Medicinal Chemistry, 2022 - ingentaconnect.com
Indole (2, 3-benzopyrrole) containing a pyrrolyl ring possesses the characteristic of electron-
rich aromatic compounds. Indole occurs in the oil of jasmine and cloves and coal tar …

Multicomponent reaction for the synthesis of new 1, 3, 4-thiadiazole-thiazolidine-4-one molecular hybrids as promising antidiabetic agents through α-glucosidase and …

L Gummidi, N Kerru, O Ebenezer, P Awolade… - Bioorganic …, 2021 - Elsevier
A simple and efficient protocol was developed to synthesize a new library of thiazolidine-4-
one molecular hybrids (4a-n) via a one-pot multicomponent reaction involving 5-substituted …

Recent green chemistry approaches for pyrimidine derivatives as a potential anti-cancer agent: An overview (2013–2023)

K Kajal, R Shakya, M Rashid, V Nigam… - Sustainable Chemistry …, 2024 - Elsevier
The widespread scrutiny of orthodox synthetic techniques for the fabrication of nitrogen-
embracing heteroatom segments has shifted scholar's focus to innovative environmentally …

Diaza-1, 3-butadienes as useful intermediate in heterocycles synthesis

J Heredia-Moya, DA Zurita, JE Cadena-Cruz… - Molecules, 2022 - mdpi.com
Many heterocyclic compounds can be synthetized using diaza-1, 3-butadienes (DADs) as
key structural precursors. Isolated and in situ diaza-1, 3-butadienes, produced from their …

Enchant OH⋅⋅⋅ O interactions in hydrated 6-amino-2-methoxypyrimidin-4 (3H) one resembles as water flow in the channel: crystallographic and theoretical …

J Jayashankar, MK Hema, CS Karthik, D Suma… - Journal of Molecular …, 2022 - Elsevier
In this present investigation, a hydrated single crystal of new, 6-amino-2-methoxypyrimidin-4
(3 H) one (AMP) has been grown using slow solvent evaporation technique. The single …

Design, synthesis and cytotoxic evaluation of a library of oxadiazole-containing hybrids

CM Camacho, MG Pizzio, DL Roces, DB Boggián… - RSC …, 2021 - pubs.rsc.org
The development of hybrid compounds led to the discovery of new pharmacologically active
agents for some of the most critical diseases, including cancer. Herein, we describe a new …

Investigation of the Vibrational Characteristics of 6-Isocyano-1-Methyl-1H-Indole: Utilizing the Isonitrile Group as an Infrared Probe

M You, Z Gao, L Zhou, C Guo, Q Guo - Molecules, 2023 - mdpi.com
Indole derivatives have garnered considerable attention in the realm of biochemistry due to
their multifaceted properties. In this study, we undertake a systematic investigation of the …

Design and synthesis of new nicotinamide derivatives generated via Suzuki Miyaura coupling as potential anticancer hits targeting pancreatic cancer cell line MIA …

L Vedavi, A Rahman, PS Rajaput, BN Nippu… - Journal of Molecular …, 2024 - Elsevier
Pancreatic cancer is one of the most fatal malignancies with low survival rate and spreads
asymptomatically due to the intensive involvement and expression of PARP1 protein …

Green Synthesis of Novel [1,3,4]Thiadiazolo[3,2-a]Pyrimidines via Three-Component Reaction of 5-Amino-1,3,4-Thiadiazole-2-Thiol, Aromatic Aldehydes, and …

F Alizadeh-Bami, H Mehrabi - Polycyclic Aromatic Compounds, 2023 - Taylor & Francis
A novel and highly efficient synthetic route to [1, 3, 4] thiadiazolo [3, 2-a] pyrimidine
derivatives from 5-amino-1, 3, 4-thiadiazole-2-thiol, various aromatic aldehydes, and …