A quality by design approach in oral extended release drug delivery systems: where we are and where we are going?

AS Sousa, J Serra, C Estevens, R Costa… - Journal of …, 2023 - Springer
Background Oral extended release (ER) delivery systems have quickly gained increasing
importance because of their ability to maintain drug levels in the blood more consistently …

Green fluorescence-based approaches for quantitative estimation of the antihistaminic drug meclizine; application to spiked human plasma

EA Ghozzy, NM El-Enany, MM Tolba… - … Chemistry and Pharmacy, 2024 - Elsevier
Meclizine hydrochloride (MCZ) is a sedating antihistamine having anti-muscarinic
properties. It is mainly recognized for its antiemetic properties. Two eco-friendly, facile, and …

Oral pH triggered colon-specific ketoprofen loaded microspheres for the better management of early morning symptoms associated with rheumatoid arthritis. Part I …

K Sanka, PR Veerareddy… - Journal of Dispersion …, 2024 - Taylor & Francis
The primary goal of this research was to investigate pH-triggered colon-specific ketoprofen-
loaded microspheres (C-SKLM) using Eudragit S-100 as a pH-dependent polymer. The …

Development of a patient-centric formulation of tegoprazan, a novel potassium-competitive acid blocker, using modified-release drug-coated pellets

SC Lee, M Kim, D Kim, EK Jeon, EH Lee - Journal of Pharmaceutical …, 2022 - Springer
Purpose The purpose of this study was to develop a patient-centric formulation of
tegoprazan, a novel potassium-competitive acid blocker, using modified-release drug …

Development of a quality by design based hybrid RP-HPLC method for Glimepiride: Bioanalytical and industrial applications

A Kumar, C Dhiman, M Kumar… - Journal of Applied …, 2025 - japsonline.com
In this study, we present a hybrid analytical method for the quantification of glimepiride
(GLP) from blood plasma and pharmaceutical formulations. Shimadzu HPLC (Model SIL 20 …

Molecular and Circuit Mechanisms Regulating Nausea and Vomiting: Recent Advances and Future Perspectives

S Xu, G Zhou, B Wu, TT Liu - Neuropharmacology and Therapy, 2024 - scienceopen.com
Nausea and vomiting are closely related but distinct physiologic and psychological
phenomena that are often experienced together. The incidence of nausea and vomiting are …