Reactive astrocyte nomenclature, definitions, and future directions
Reactive astrocytes are astrocytes undergoing morphological, molecular, and functional
remodeling in response to injury, disease, or infection of the CNS. Although this remodeling …
remodeling in response to injury, disease, or infection of the CNS. Although this remodeling …
Human organoids in basic research and clinical applications
Organoids are three-dimensional (3D) miniature structures cultured in vitro produced from
either human pluripotent stem cells (hPSCs) or adult stem cells (AdSCs) derived from …
either human pluripotent stem cells (hPSCs) or adult stem cells (AdSCs) derived from …
INVESTIGATING MEMORY LOSS: HOW DEPRESSION AFFECTS STUDENTS'MEMORY ENDURANCE
A Aprilia, D Aminatun - Journal of English Language Teaching …, 2022 - jim.teknokrat.ac.id
Depression is a disorder that affects feelings and thoughts in the form of feelings of
continuous sadness and a sense of loss of interest before doing an activity. One of the …
continuous sadness and a sense of loss of interest before doing an activity. One of the …
[HTML][HTML] A transcription factor atlas of directed differentiation
Transcription factors (TFs) regulate gene programs, thereby controlling diverse cellular
processes and cell states. To comprehensively understand TFs and the programs they …
processes and cell states. To comprehensively understand TFs and the programs they …
Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids
Brain organoids derived from human pluripotent stem cells provide a highly valuable in vitro
model to recapitulate human brain development and neurological diseases. However, the …
model to recapitulate human brain development and neurological diseases. However, the …
[HTML][HTML] Organoid intelligence (OI): the new frontier in biocomputing and intelligence-in-a-dish
Biological computing (or biocomputing) offers potential advantages over silicon-based
computing in terms of faster decision-making, continuous learning during tasks, and greater …
computing in terms of faster decision-making, continuous learning during tasks, and greater …
Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex
Realizing the full utility of brain organoids to study human development requires
understanding whether organoids precisely replicate endogenous cellular and molecular …
understanding whether organoids precisely replicate endogenous cellular and molecular …
Generation of vascularized brain organoids to study neurovascular interactions
XY Sun, XC Ju, Y Li, PM Zeng, J Wu, YY Zhou… - elife, 2022 - elifesciences.org
Brain organoids have been used to recapitulate the processes of brain development and
related diseases. However, the lack of vasculatures, which regulate neurogenesis and brain …
related diseases. However, the lack of vasculatures, which regulate neurogenesis and brain …
Is it time to start transitioning from 2D to 3D cell culture?
Cell culture is an important and necessary process in drug discovery, cancer research, as
well as stem cell study. Most cells are currently cultured using two-dimensional (2D) …
well as stem cell study. Most cells are currently cultured using two-dimensional (2D) …
Long-term maturation of human cortical organoids matches key early postnatal transitions
Human stem-cell-derived models provide the promise of accelerating our understanding of
brain disorders, but not knowing whether they possess the ability to mature beyond mid-to …
brain disorders, but not knowing whether they possess the ability to mature beyond mid-to …