The biological basis for cardiac repair after myocardial infarction: from inflammation to fibrosis
In adult mammals, massive sudden loss of cardiomyocytes after infarction overwhelms the
limited regenerative capacity of the myocardium, resulting in the formation of a collagen …
limited regenerative capacity of the myocardium, resulting in the formation of a collagen …
Cardioimmunology: the immune system in cardiac homeostasis and disease
The past few decades have generated growing recognition that the immune system makes
an important contribution to cardiac development, composition and function. Immune cells …
an important contribution to cardiac development, composition and function. Immune cells …
Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction
SA Dick, JA Macklin, S Nejat, A Momen… - Nature …, 2019 - nature.com
Macrophages promote both injury and repair after myocardial infarction, but discriminating
functions within mixed populations remains challenging. Here we used fate map** …
functions within mixed populations remains challenging. Here we used fate map** …
Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure
Cardiovascular diseases claim more lives worldwide than any other. Etiologically, the
dominant trajectory involves atherosclerosis, a chronic inflammatory process of lipid-rich …
dominant trajectory involves atherosclerosis, a chronic inflammatory process of lipid-rich …
Chronic heart failure and inflammation: what do we really know?
SA Dick, S Epelman - Circulation research, 2016 - Am Heart Assoc
As a greater proportion of patients survive their initial cardiac insult, medical systems
worldwide are being faced with an ever-growing need to understand the mechanisms …
worldwide are being faced with an ever-growing need to understand the mechanisms …