The multifaceted role of vitamin B6 in cancer: Drosophila as a model system to investigate DNA damage

R Contestabile, ML di Salvo, V Bunik… - Open …, 2020 - royalsocietypublishing.org
A perturbed uptake of micronutrients, such as minerals and vitamins, impacts on different
human diseases, including cancer and neurological disorders. Several data converge …

The effect of taxifolin on cisplatin‐induced pulmonary damage in rats: a biochemical and histopathological evaluation

E Unver, M Tosun, H Olmez, M Kuzucu… - Mediators of …, 2019 - Wiley Online Library
The effect of taxifolin on cisplatin‐induced oxidative pulmonary damage was investigated
biochemically and histopathologically in male albino Wistar rats. There were four groups …

Apocynin alleviates cisplatin‐induced testicular cytotoxicity by regulating oxidative stress and apoptosis in rats

KM Köroğlu, Ö Çevik, G Şener, F Ercan - Andrologia, 2019 - Wiley Online Library
The aim of this study was to investigate possible protective effects of apocynin (APO), an
NADPH oxidase (NOX2) inhibitor, on cisplatin (CIS)‐induced testicular damage. Four …

Apelin-13 attenuates cisplatin-induced cardiotoxicity through inhibition of ROS-mediated DNA damage and regulation of MAPKs and AKT pathways

P Zhang, L Yi, G Meng, H Zhang, H Sun… - Free radical …, 2017 - Taylor & Francis
Platinum-based chemotherapy represents one of the most effective ways in combating
human cancers. However, the cardiotoxicity subsequent severely limited its clinical …

The beneficial effects of sulfur-containing amino acids on cisplatininduced cardiotoxicity and neurotoxicity in rodents

G Rosic, J Joksimovic, D Selakovic… - Current Medicinal …, 2018 - benthamdirect.com
Background: Cisplatin is one the most frequently used chemotherapeutic drugs for several
decades. Although its antineoplastic effect has been reported in treatment of numerous …

Based on network pharmacology and molecular docking to explore the protective effect of Epimedii Folium extract on cisplatin-induced intestinal injury in mice

J **a, JN Hu, Z Wang, EB Cai, S Ren… - Frontiers in …, 2022 - frontiersin.org
Background: Epimedii Folium, as a natural botanical medicine, has been reported to have
protective effects on intestinal diseases by modulating multiple signaling pathways. This …

Characterization of cardiovascular alterations induced by different chronic cisplatin treatments

E Herradón, C González, JA Uranga, R Abalo… - Frontiers in …, 2017 - frontiersin.org
In the last years, many clinical studies have revealed that some cisplatin-treated cancer
survivors have a significantly increased risk of cardiovascular events, being cisplatin …

Effect of lycopene on oxidative ovary-damage induced by cisplatin in rats.

N Kulhan, M Kulhan, CAN TÜRKLER… - General physiology …, 2019 - avesis.ebyu.edu.tr
The anti-cancer drugs, particularly those used in reproductive period, may cause several
complications such as ovarian insufficiency and infertility. The mechanism of action of …

[HTML][HTML] The effect of taxifolin on high-dose-cisplatin-induced oxidative liver injury in rats

N Kurt, ÖN Türkeri, B Suleyman… - Advances in Clinical …, 2021 - advances.umw.edu.pl
Background. Cisplatin is a non-specific platinum-based (derivative) chemotherapeutic agent
that causes an increase in free radicals activity in the liver. Antio xidant activity of taxifolin …

[PDF][PDF] Fertility protective effect of taxifolin in cisplatin-induced ovarian damage.

R Ozyurt, N Celik, Z Suleyman, F Cagiran… - European Review for …, 2022 - researchgate.net
OBJECTIVE: The aim of our study was to investigate the protective effect of taxifolin on
ovarian damage and reproductive dysfunction created by cisplatin administration …