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Tutorial: a guide for the selection of fast and accurate computational tools for the prediction of intrinsic disorder in proteins
Intrinsic disorder is instrumental for a wide range of protein functions, and its analysis, using
computational predictions from primary structures, complements secondary and tertiary …
computational predictions from primary structures, complements secondary and tertiary …
Computational prediction of disordered binding regions
One of the key features of intrinsically disordered regions (IDRs) is their ability to interact
with a broad range of partner molecules. Multiple types of interacting IDRs were identified …
with a broad range of partner molecules. Multiple types of interacting IDRs were identified …
DEPICTER2: a comprehensive webserver for intrinsic disorder and disorder function prediction
Intrinsic disorder in proteins is relatively abundant in nature and essential for a broad
spectrum of cellular functions. While disorder can be accurately predicted from protein …
spectrum of cellular functions. While disorder can be accurately predicted from protein …
Comparative evaluation of AlphaFold2 and disorder predictors for prediction of intrinsic disorder, disorder content and fully disordered proteins
We expand studies of AlphaFold2 (AF2) in the context of intrinsic disorder prediction by
comparing it against a broad selection of 20 accurate, popular and recently released …
comparing it against a broad selection of 20 accurate, popular and recently released …
HybridRNAbind: prediction of RNA interacting residues across structure-annotated and disorder-annotated proteins
The sequence-based predictors of RNA-binding residues (RBRs) are trained on either
structure-annotated or disorder-annotated binding regions. A recent study of predictors of …
structure-annotated or disorder-annotated binding regions. A recent study of predictors of …
[HTML][HTML] Compositional bias of intrinsically disordered proteins and regions and their predictions
Intrinsically disordered regions (IDRs) carry out many cellular functions and vary in length
and placement in protein sequences. This diversity leads to variations in the underlying …
and placement in protein sequences. This diversity leads to variations in the underlying …
Identification of the RSX interactome in a marsupial shows functional coherence with the **st interactome during X inactivation
The marsupial specific RSX lncRNA is the functional analogue of the eutherian specific
XIST, which coordinates X chromosome inactivation. We characterized the RSX interactome …
XIST, which coordinates X chromosome inactivation. We characterized the RSX interactome …
Resources for computational prediction of intrinsic disorder in proteins
L Kurgan - Methods, 2022 - Elsevier
With over 40 years of research, researchers in the intrinsic disorder prediction field
developed over 100 computational predictors. This review offers a holistic perspective of this …
developed over 100 computational predictors. This review offers a holistic perspective of this …
An atlas of posttranslational modifications on RNA binding proteins
RNA structure and function are intimately tied to RNA binding protein recognition and
regulation. Posttranslational modifications are chemical modifications which can control …
regulation. Posttranslational modifications are chemical modifications which can control …
CLIP: accurate prediction of disordered linear interacting peptides from protein sequences using co-evolutionary information
One of key features of intrinsically disordered regions (IDRs) is facilitation of protein–protein
and protein–nucleic acids interactions. These disordered binding regions include molecular …
and protein–nucleic acids interactions. These disordered binding regions include molecular …