[HTML][HTML] The papillomavirus E7 proteins

A Roman, K Munger - Virology, 2013 - Elsevier
E7 is an accessory protein that is not encoded by all papillomaviruses. The E7 amino
terminus contains two regions of similarity to conserved regions 1 and 2 of the adenovirus …

Molecular mechanisms of human papillomavirus induced skin carcinogenesis

M Hufbauer, B Akgül - Viruses, 2017 - mdpi.com
Infection of the cutaneous skin with human papillomaviruses (HPV) of genus
betapapillomavirus (βHPV) is associated with the development of premalignant actinic …

Association between β-genus human papillomavirus and cutaneous squamous cell carcinoma in immunocompetent individuals—a meta-analysis

J Chahoud, A Semaan, Y Chen, M Cao… - JAMA …, 2016 - jamanetwork.com
Importance Existing epidemiological evidence remains controversial regarding the
association between β-genus human papillomavirus (β-HPV) and cutaneous squamous cell …

[HTML][HTML] Small DNA tumor viruses and human cancer: Preclinical models of virus infection and disease

ME Spurgeon - Tumour Virus Research, 2022 - Elsevier
Human tumor viruses cause various human cancers that account for at least 15% of the
global cancer burden. Among the currently identified human tumor viruses, two are small …

Transcription properties of beta-HPV8 and HPV38 Genomes in human keratinocytes

TM Rehm, E Straub, S Forchhammer, U Leiter… - Journal of …, 2022 - Am Soc Microbiol
Persistent infections with high-risk human papillomaviruses (HR-HPV) from the genus alpha
are established risk factors for the development of anogenital and oropharyngeal cancers. In …

Loss of genome fidelity: beta HPVs and the DNA damage response

SO Wendel, NA Wallace - Frontiers in Microbiology, 2017 - frontiersin.org
While the role of genus alpha human papillomaviruses in the tumorigenesis and tumor
maintenance of anogenital and oropharyngeal cancers is well-established, the role of genus …

Beta HPV deregulates double-strand break repair

C Hu, N Wallace - Viruses, 2022 - mdpi.com
Beta human papillomavirus (beta HPV) infections are common in adults. Certain types of
beta HPVs are associated with nonmelanoma skin cancer (NMSC) in immunocompromised …

Mucosal alpha‐papillomaviruses are not associated with esophageal squamous cell carcinomas: Lack of mechanistic evidence from S outh A frica, C hina and I ran …

G Halec, M Schmitt, S Egger, CC Abnet… - … journal of cancer, 2016 - Wiley Online Library
Epidemiological and mechanistic evidence on the causative role of human papillomaviruses
(HPV) in esophageal squamous cell carcinoma (ESCC) is unclear. We retrieved alcohol …

Why responses to immune checkpoint inhibitors are heterogeneous in head and neck cancers: Contributions from tumor-intrinsic and host-intrinsic factors

Z Chen, J John, JH Wang - Frontiers in Oncology, 2022 - frontiersin.org
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment including in head
and neck squamous cell carcinomas (HNSCCs); however, only a fraction of HNSCC patients …

A functional interaction of E7 with B-Myb-MuvB complex promotes acute cooperative transcriptional activation of both S-and M-phase genes.(129 c)

CL Pang, SY Toh, P He, S Teissier, Y Ben Khalifa… - Oncogene, 2014 - nature.com
High-risk human papillomaviruses are causative agents of cervical cancer. Viral protein E7
is required to establish and maintain the pro-oncogenic phenotype in infected cells, but the …