Multienzyme‐like nanozymes: regulation, rational design, and application

J Sheng, Y Wu, H Ding, K Feng, Y Shen… - Advanced …, 2024‏ - Wiley Online Library
Nanomaterials with more than one enzyme‐like activity are termed multienzymic
nanozymes, and they have received increasing attention in recent years and hold huge …

Recent advances in nanozymes: from matters to bioapplications

Y Ai, ZN Hu, X Liang, H Sun, H **n… - Advanced Functional …, 2022‏ - Wiley Online Library
The manufacture of bionic materials to simulate the natural counterparts has attracted
extensive attention. As one of the subcategories of biomimetic materials, the development of …

Artificial nonenzymatic antioxidant MXene nanosheet-anchored injectable hydrogel as a mild photothermal-controlled oxygen release platform for diabetic wound …

Y Li, R Fu, Z Duan, C Zhu, D Fan - Acs Nano, 2022‏ - ACS Publications
Hypoxia, excessive reactive oxygen species (ROS), impaired angiogenesis, lasting
inflammation, and bacterial infection, are key problems impeding diabetic wound healing …

Nanozymes: Activity origin, catalytic mechanism, and biological application

W Yang, X Yang, L Zhu, H Chu, X Li, W Xu - Coordination Chemistry …, 2021‏ - Elsevier
Nanozymes are nanomaterials with excellent enzyme-like characteristics. Compared with
natural enzymes, nanozymes possess significant advantages, such as low cost, high …

Reaction mechanisms and kinetics of nanozymes: insights from theory and computation

X Shen, Z Wang, XJ Gao, X Gao - Advanced Materials, 2024‏ - Wiley Online Library
Abstract “Nanozymes” usually refers to inorganic nanomaterials with enzyme‐like catalytic
activities. The research into nanozymes is one of the hot topics on the horizon of …

A review on metal-and metal oxide-based nanozymes: properties, mechanisms, and applications

Q Liu, A Zhang, R Wang, Q Zhang, D Cui - Nano-micro letters, 2021‏ - Springer
Since the ferromagnetic (Fe 3 O 4) nanoparticles were firstly reported to exert enzyme-like
activity in 2007, extensive research progress in nanozymes has been made with deep …

Bioactive NIR-II gold clusters for three-dimensional imaging and acute inflammation inhibition

H Ma, X Zhang, L Liu, Y Huang, S Sun, K Chen… - Science …, 2023‏ - science.org
Strong fluorescence and high catalytic activities cannot be achieved simultaneously due to
conflicts in free electron utilization, resulting in a lack of bioactivity of most near-infrared-II …

Antioxidant and Prooxidant Nanozymes: From Cellular Redox Regulation to Next‐Generation Therapeutics

N Singh, GR Sherin, G Mugesh - Angewandte Chemie, 2023‏ - Wiley Online Library
Nanozymes, nanomaterials with enzyme‐mimicking activity, have attracted tremendous
interest in recent years owing to their ability to replace natural enzymes in various …

Customized intranasal hydrogel delivering methylene blue ameliorates cognitive dysfunction against Alzheimer's disease

Y Liu, Y Tan, G Cheng, Y Ni, A **e, X Zhu… - Advanced …, 2024‏ - Wiley Online Library
The accumulation of hyperphosphorylated tau protein aggregates is a key pathogenic event
in Alzheimer's disease (AD) and induces mitochondrial dysfunction and reactive oxygen …

Nanozyme-based strategies for efficient theranostics of brain diseases

R Xu, S Zhang, P Wang, R Zhang, P Lin, Y Wang… - Coordination Chemistry …, 2024‏ - Elsevier
Oxidative stress emerges as a critical mechanism underlying the development and
progression of various brain diseases, arising from either increased generation of reactive …