As an important economic insect, silkworm Bombyx mori (L.)(Lepidoptera: Bombycidae) has
numerous advantages in life science, such as low breeding cost, large progeny size, short …

Unlike superficial fungal infections of the skin and nails, which are the most common fungal
diseases in humans, invasive fungal infections carry high morbidity and mortality …

The demand for novel antibiotics to combat the global spread of multi drug-resistant
pathogens continues to grow. Pathogenic bacteria and fungi that cause fatal human …

Abstract Bombyx mori Linnaeus, 1758 (Lepidoptera: Bombycidae), a very important
economical insect and backbone of the silk industry, is fully reliant on humans for its life …

Silkworm, Bombyx mori, has various advantages as an experimental animal, such as the low
cost for rearing and fewer ethical problems. Models utilizing silkworms of infection with …

Candida auris is an emerging fungal pathogen that is feared to spread of infection because
of its propensity for multidrug resistance and high mortality rate. This pathogenic yeast is …

Trichosporon asahii is a conditional pathogenic fungus that causes severe and sometimes
fatal infections in immunocompromised patients. While calcineurin, an essential component …

The development of novel antimicrobial agents is required to solve the problem of
antimicrobial resistance. We established a quantitative method for evaluating the therapeutic …

Drugs are developed through basic studies and clinical trials. In basic studies, researchers
seek drug candidates using in vitro evaluation systems and subsequently examine their …

Animal models of pathogenic infection are needed to evaluate candidate compounds for the
development of anti-infectious drugs. Dermatophytes are pathogenic fungi that cause …