PLGA-based nanomedicine: history of advancement and development in clinical applications of multiple diseases

HO Alsaab, FD Alharbi, AS Alhibs, NB Alanazi… - Pharmaceutics, 2022‏ - mdpi.com
Research on the use of biodegradable polymers for drug delivery has been ongoing since
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …

Structure‐based varieties of polymeric nanocarriers and influences of their physicochemical properties on drug delivery profiles

R De, MK Mahata, KT Kim - Advanced Science, 2022‏ - Wiley Online Library
Carriers are equally important as drugs. They can substantially improve bioavailability of
cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently …

Nanoparticles in the diagnosis and treatment of vascular aging and related diseases

H Xu, S Li, YS Liu - Signal Transduction and Targeted Therapy, 2022‏ - nature.com
Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …

Advances in the treatment of atherosclerosis with ligand‐modified nanocarriers

X Deng, J Wang, S Yu, S Tan, T Yu, Q Xu, N Chen… - …, 2024‏ - Wiley Online Library
Atherosclerosis, a chronic disease associated with metabolism, poses a significant risk to
human well‐being. Currently, existing treatments for atherosclerosis lack sufficient efficiency …

Enzyme catalysis biomotor engineering of neutrophils for nanodrug delivery and cell-based thrombolytic therapy

J Zheng, R Qi, C Dai, G Li, M Sang - ACS nano, 2022‏ - ACS Publications
Utilizing neutrophils (NEs) to target and deliver nanodrugs to inflammation sites has
received considerable attention. NEs are involved in the formation and development of …

[HTML][HTML] Lipid-based nanotechnology: Liposome

Y Jiang, W Li, Z Wang, J Lu - Pharmaceutics, 2023‏ - mdpi.com
Over the past several decades, liposomes have been extensively developed and used for
various clinical applications such as in pharmaceutical, cosmetic, and dietetic fields, due to …

Nanotechnology in drug and gene delivery

S Hamimed, M Jabberi, A Chatti - Naunyn-schmiedeberg's Archives of …, 2022‏ - Springer
Over the last decade, nanotechnology has widely addressed many nanomaterials in the
biomedical area with an opportunity to achieve better-targeted delivery, effective treatment …

Transcriptional co-activators: emerging roles in signaling pathways and potential therapeutic targets for diseases

PD Talukdar, U Chatterji - Signal transduction and targeted therapy, 2023‏ - nature.com
Specific cell states in metazoans are established by the symphony of gene expression
programs that necessitate intricate synergic interactions between transcription factors and …

[HTML][HTML] Advances in drug delivery to atherosclerosis: Investigating the efficiency of different nanomaterials employed for different type of drugs

B Perera, Y Wu, NT Nguyen, HT Ta - Materials Today Bio, 2023‏ - Elsevier
Atherosclerosis is the build-up of fatty deposits in the arteries, which is the main underlying
cause of cardiovascular diseases and the leading cause of global morbidity and mortality …

Nanomedicine and nanotheranostics: special focus on imaging of anticancer drugs induced cardiac toxicity

A Setia, RR Challa, B Vallamkonda, P Satti… - …, 2024‏ - pmc.ncbi.nlm.nih.gov
Cardiotoxicity, the often-overlooked second leading cause of death in cancer patients, has
been associated with certain anticancer drugs. These drugs can induce cardiac damage …