Formation and integration of new neurons in the adult hippocampus

A Denoth-Lippuner, S Jessberger - Nature Reviews Neuroscience, 2021 - nature.com
Neural stem cells (NSCs) generate new neurons throughout life in the mammalian brain.
Adult-born neurons shape brain function, and endogenous NSCs could potentially be …

Arc/Arg3. 1 function in long‐term synaptic plasticity: Emerging mechanisms and unresolved issues

H Zhang, CR Bramham - European Journal of Neuroscience, 2021 - Wiley Online Library
Arc (activity‐regulated cytoskeleton‐associated protein) is posited as a critical regulator of
long‐term synaptic plasticity at excitatory synapses, including long‐term potentiation, long …

Adult-born hippocampal neurons undergo extended development and are morphologically distinct from neonatally-born neurons

JD Cole, DF Espinueva, DR Seib, AM Ash… - Journal of …, 2020 - Soc Neuroscience
During immature stages, adult-born neurons pass through critical periods for survival and
plasticity. It is generally assumed that by 2 months of age adult-born neurons are mature and …

The dendritic engram

G Kastellakis, S Tasciotti, I Pandi… - Frontiers in Behavioral …, 2023 - frontiersin.org
Accumulating evidence from a wide range of studies, including behavioral, cellular,
molecular and computational findings, support a key role of dendrites in the encoding and …

Transcriptional dynamics orchestrating the development and integration of neurons born in the adult hippocampus

NB Rasetto, D Giacomini, AA Berardino… - Science …, 2024 - science.org
The adult hippocampus generates new granule cells (aGCs) with functional capabilities that
convey unique forms of plasticity to the preexisting circuits. While early differentiation of adult …

Adult hippocampal neurogenesis in the context of lipopolysaccharide-induced neuroinflammation: a molecular, cellular and behavioral review

E Domínguez-Rivas, E Ávila-Muñoz… - Brain, Behavior, and …, 2021 - Elsevier
The continuous generation of new neurons occurs in at least two well-defined niches in the
adult rodent brain. One of these areas is the subgranular zone of the dentate gyrus (DG) in …
KR Jenks, K Tsimring, JPK Ip, JC Zepeda… - Frontiers in neural …, 2021 - frontiersin.org
Neurons remodel the structure and strength of their synapses during critical periods of
development in order to optimize both perception and cognition. Many of these …

Adult hippocampal neurogenesis in different taxonomic groups: possible functional similarities and striking controversies

M Augusto-Oliveira, GPF Arrifano, JO Malva… - Cells, 2019 - mdpi.com
Adult neurogenesis occurs in many species, from fish to mammals, with an apparent
reduction in the number of both neurogenic zones and new neurons inserted into …