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Acute respiratory distress syndrome: causes, pathophysiology, and phenotypes
LDJ Bos, LB Ware - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is a common clinical syndrome of acute
respiratory failure as a result of diffuse lung inflammation and oedema. ARDS can be …
respiratory failure as a result of diffuse lung inflammation and oedema. ARDS can be …
Pulmonary surfactant: a mighty thin film
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
Acute respiratory distress syndrome
KD Wick, LB Ware, MA Matthay - bmj, 2024 - bmj.com
The understanding of acute respiratory distress syndrome (ARDS) has evolved greatly since
it was first described in a 1967 case series, with several subsequent updates to the definition …
it was first described in a 1967 case series, with several subsequent updates to the definition …
Endothelial dysfunction triggers acute respiratory distress syndrome in patients with sepsis: a narrative review
Acute respiratory distress syndrome (ARDS) is a severe organ failure occurring mainly in
critically ill patients as a result of different types of insults such as sepsis, trauma or …
critically ill patients as a result of different types of insults such as sepsis, trauma or …
[HTML][HTML] The role of the alveolar epithelial glycocalyx in acute respiratory distress syndrome
AN Rizzo, EP Schmidt - American Journal of Physiology …, 2023 - journals.physiology.org
The alveolar epithelial glycocalyx is a dense anionic layer of glycosaminoglycans (GAGs)
and proteoglycans that lines the apical surface of the alveolar epithelium. In contrast to the …
and proteoglycans that lines the apical surface of the alveolar epithelium. In contrast to the …
The influenza-injured lung microenvironment promotes MRSA virulence, contributing to severe secondary bacterial pneumonia
C Langouët-Astrié, K Oshima, SA McMurtry, Y Yang… - Cell reports, 2022 - cell.com
Influenza infection is substantially worsened by the onset of secondary pneumonia caused
by bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA). The bidirectional …
by bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA). The bidirectional …
N‐Acetylcysteine and Other Sulfur‐Donors as a Preventative and Adjunct Therapy for COVID‐19
The airway epithelial glycocalyx plays an important role in preventing severe acute
respiratory syndrome coronavirus 2 entry into the epithelial cells, while the endothelial …
respiratory syndrome coronavirus 2 entry into the epithelial cells, while the endothelial …
Advancing precision medicine for the diagnosis and treatment of acute respiratory distress syndrome
AN Rizzo, NR Aggarwal, BT Thompson… - Journal of Clinical …, 2023 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a common and life-threatening cause of
respiratory failure. Despite decades of research, there are no effective pharmacologic …
respiratory failure. Despite decades of research, there are no effective pharmacologic …
[HTML][HTML] New insights into the alveolar epithelium as a driver of acute respiratory distress syndrome
The alveolar epithelium serves as a barrier between the body and the external environment.
To maintain efficient gas exchange, the alveolar epithelium has evolved to withstand and …
To maintain efficient gas exchange, the alveolar epithelium has evolved to withstand and …
[HTML][HTML] Engineering of pulmonary surfactant corona on inhaled nanoparticles to operate in the lung system
Exposure of inhaled nanoparticles (NPs) to the deep lung tissue results in the adsorption of
pulmonary surfactant (PSf) on the surface of NPs and the formation of a biomolecular …
pulmonary surfactant (PSf) on the surface of NPs and the formation of a biomolecular …