A theory of biological relativity: no privileged level of causation
Must higher level biological processes always be derivable from lower level data and
mechanisms, as assumed by the idea that an organism is completely defined by its …
mechanisms, as assumed by the idea that an organism is completely defined by its …
Systems biology, proteomics, and the future of health care: toward predictive, preventative, and personalized medicine
The emergence of systems biology is bringing forth a new set of challenges for advancing
science and technology. Defining ways of studying biological systems on a global level …
science and technology. Defining ways of studying biological systems on a global level …
The “domestication syndrome” in mammals: a unified explanation based on neural crest cell behavior and genetics
Charles Darwin, while trying to devise a general theory of heredity from the observations of
animal and plant breeders, discovered that domesticated mammals possess a distinctive …
animal and plant breeders, discovered that domesticated mammals possess a distinctive …
[HTML][HTML] Circuitry and dynamics of human transcription factor regulatory networks
The combinatorial cross-regulation of hundreds of sequence-specific transcription factors
(TFs) defines a regulatory network that underlies cellular identity and function. Here we use …
(TFs) defines a regulatory network that underlies cellular identity and function. Here we use …
[کتاب][B] The regulatory genome: gene regulatory networks in development and evolution
EH Davidson - 2010 - books.google.com
Gene regulatory networks are the most complex, extensive control systems found in nature.
The interaction between biology and evolution has been the subject of great interest in …
The interaction between biology and evolution has been the subject of great interest in …
The Genome of the Sea Urchin Strongylocentrotus purpuratus
We report the sequence and analysis of the 814-megabase genome of the sea urchin
Strongylocentrotus purpuratus, a model for developmental and systems biology. The …
Strongylocentrotus purpuratus, a model for developmental and systems biology. The …
Gene regulatory networks for development
M Levine, EH Davidson - Proceedings of the National …, 2005 - National Acad Sciences
The genomic program for development operates primarily by the regulated expression of
genes encoding transcription factors and components of cell signaling pathways. This …
genes encoding transcription factors and components of cell signaling pathways. This …
[HTML][HTML] Apical constriction: a cell shape change that can drive morphogenesis
JM Sawyer, JR Harrell, G Shemer… - Developmental …, 2010 - Elsevier
Biologists have long recognized that dramatic bending of a cell sheet may be driven by even
modest shrinking of the apical sides of cells. Cell shape changes and tissue movements like …
modest shrinking of the apical sides of cells. Cell shape changes and tissue movements like …
The coherent feedforward loop serves as a sign-sensitive delay element in transcription networks
Recent analysis of the structure of transcription regulation networks revealed several
“network motifs”: regulatory circuit patterns that occur much more frequently than in …
“network motifs”: regulatory circuit patterns that occur much more frequently than in …
Can a biologist fix a radio?—Or, what I learned while studying apoptosis
Y Lazebnik - Cancer cell, 2002 - cell.com
As a freshly minted Assistant Professor, I feared that everything in my field would be
discovered before I even had a chance to set up my laboratory. Indeed, the field of …
discovered before I even had a chance to set up my laboratory. Indeed, the field of …