Psychopathy

SA De Brito, AE Forth, AR Baskin-Sommers… - Nature Reviews …, 2021 - nature.com
Psychopathy is a personality disorder characterized by a constellation of affective,
interpersonal, lifestyle and antisocial features whose antecedents can be identified in a …

Conduct disorder

G Fairchild, DJ Hawes, PJ Frick… - Nature Reviews …, 2019 - nature.com
Conduct disorder (CD) is a common and highly impairing psychiatric disorder that usually
emerges in childhood or adolescence and is characterized by severe antisocial and …

Neurodevelopmental disorders and environmental toxicants: epigenetics as an underlying mechanism

NQV Tran, K Miyake - International journal of genomics, 2017 - Wiley Online Library
The increasing prevalence of neurodevelopmental disorders, especially autism spectrum
disorders (ASD) and attention deficit hyperactivity disorder (ADHD), calls for more research …

The role of epigenetic change in autism spectrum disorders

YJ Loke, AJ Hannan, JM Craig - Frontiers in neurology, 2015 - frontiersin.org
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental
disorders characterized by problems with social communication, social interaction, and …

Epigenetic profiling of ADHD symptoms trajectories: a prospective, methylome-wide study

E Walton, JB **ault, CAM Cecil, TR Gaunt… - Molecular …, 2017 - nature.com
Attention-deficit/hyperactivity disorder (ADHD) is a prevalent developmental disorder,
associated with a range of long-term impairments. Variation in DNA methylation, an …

Childhood maternal care is associated with DNA methylation of the genes for brain-derived neurotrophic factor (BDNF) and oxytocin receptor (OXTR) in peripheral …

E Unternaehrer, AH Meyer, SCA Burkhardt… - Stress, 2015 - Taylor & Francis
In adults, reporting low and high maternal care in childhood, we compared DNA methylation
in two stress-associated genes (two target sequences in the oxytocin receptor gene, OXTR; …

The Sensitivity to Threat and Affiliative Reward (STAR) model and the development of callous-unemotional traits

R Waller, N Wagner - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
Research implicates callous-unemotional (CU) traits (ie, lack of empathy, prosociality, and
guilt, and reduced sensitivity to others' emotions) in the development of severe and …

The role of oxytocin receptor gene (OXTR) DNA methylation (DNAm) in human social and emotional functioning: a systematic narrative review

C Maud, J Ryan, JE McIntosh, CA Olsson - BMC psychiatry, 2018 - Springer
Abstract Background The neuropeptide Oxytocin (OXT) plays a central role in birthing,
mother-infant bonding and a broad range of related social behaviours in mammals. More …

The caring continuum: Evolved hormonal and proximal mechanisms explain prosocial and antisocial extremes

AA Marsh - Annual Review of Psychology, 2019 - annualreviews.org
Implicit in the long-standing disagreements about whether humans' fundamental nature is
predominantly caring or callous is an assumption of uniformity. This article reviews evidence …

Annual Research Review: DNA methylation as a mediator in the association between risk exposure and child and adolescent psychopathology

ED Barker, E Walton, CAM Cecil - Journal of Child Psychology …, 2018 - Wiley Online Library
Background DNA methylation (DNAm) is a potential mechanism for propagating the effects
of environmental exposures on child and adolescent mental health. In recent years, this field …