Diffusion MRI is arguably the method of choice for characterizing white matter microstructure
in vivo. Over the typical duration of diffusion encoding, the displacement of water molecules …

Pathological evaluation is the gold standard for identifying processes related to multiple
sclerosis that explain disease manifestations, and for guiding the development of new …

Objective Conventional magnetic resonance imaging (MRI) of the multiple sclerosis spinal
cord is limited by low specificity regarding the underlying pathological processes, and new …

Tissue microstructure modeling of diffusion MRI signal is an active research area striving to
bridge the gap between macroscopic MRI resolution and cellular-level tissue architecture …

Biophysical modelling of diffusion MRI is necessary to provide specific microstructural tissue
properties. However, estimating model parameters from data with limited diffusion gradient …

Alzheimer's disease (AD) is a progressive neurodegenerative disease, and the development
of AD is irreversible. However, preventive measures in the presymptomatic stage of AD can …

In vivo histology using magnetic resonance imaging (MRI) is a newly emerging research
field that aims to non-invasively characterize tissue microstructure. The implications of in …

Quantitative magnetic resonance imaging can be combined with advanced biophysical
models to measure microstructural features of white matter. Non-invasive microstructural …

Due to the technical challenges of large-scale microscopy and analysis, to date only limited
knowledge has been made available about axon morphometry (diameter, shape, myelin …

The VERDICT framework for modelling diffusion MRI data aims to relate parameters from a
biophysical model to histological features used for tumour grading in prostate cancer …