Anti-Parkinson potential of silymarin: Mechanistic insight and therapeutic standing

H Ullah, H Khan - Frontiers in pharmacology, 2018 - frontiersin.org
Parkinson's disease (PD) involves aggregation of α-synuclein and progressive loss of
dopaminergic neurons. Pathogenesis of PD may also be related to one's genetic …

Unveiling major ethnopharmacological aspects of genus Diospyros in context to its chemical diversity: A comprehensive overview

N Fareed, DM El‐Kersh, FS Youssef… - Journal of Food …, 2022 - Wiley Online Library
Abstract Diospyros species (DS),“Ebenaceae,” were known for their therapeutic uses in folk
medicine since days of yore. Thereafter, scientific evidence related their health benefits to a …

Antibacterial, Antifungal, Antioxidant, and Docking Studies of Potential Dinaphthodiospyrols from Diospyros lotus Linn Roots

BO Aljohny, A Rauf, Y Anwar, S Naz, A Wadood - ACS omega, 2021 - ACS Publications
The main aims of this investigation were the isolation of dimeric naphthoquinones, a new
class of dinaphthodiospyrols (1–7), from chloroform fractions and screening them for …

Electroacupuncture of the cymba concha alleviates p-chlorophenylalanine-induced insomnia in mice

F Zhang, X Zhang, Q Peng… - Acupuncture in Medicine, 2023 - journals.sagepub.com
Objective: Insomnia is the most common sleep disorder and is often comorbid with mental
and physical diseases. The present study was designed to investigate the hypnotic effect of …

Pharmaceutical Considerations of Translabial Formulations for Treatment of Parkinson's Disease: A Concept of Drug Delivery for Unconscious Patients

G Tiwari, R Tiwari, A Kaur - Current Drug Delivery, 2023 - benthamdirect.com
Purpose: The goal of the present research was to isolate a biopolymer from Phaseolus
vulgaris (P. vulgaris) and Zea mays (Z. mays) plants and used it to construct Resveratrol …

An increasing role of polyphenols as novel therapeutics for Alzheimer's: A review

N Karim, H Khan, I Khan, O Guo… - Medicinal …, 2020 - ingentaconnect.com
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder, with
approximately 29 million older people suffering from this disease worldwide. This number is …

Loading AKBA on surface of silver nanoparticles to improve their sedative-hypnotic and anti-inflammatory efficacies

A Khan, A Al-Harrasi, NU Rehman, R Sarwar… - …, 2019 - Taylor & Francis
Aim: Acetyl-11-keto-β-boswellic acid (AKBA) is a potent anti-inflammatory compound limited
by its low water solubility and bioavailability. To load AKBA on silver nanoparticles (AgNPs) …

[HTML][HTML] Sedative-hypnotic effect and in silico study of dinaphthodiospyrols isolated from Diospyros lotus Linn

YS Al-Awthan, A Rauf, U Rashid, S Bawazeer… - Biomedicine & …, 2021 - Elsevier
Abstract Traditionally, Diospyros lotus Linn is used for insomnia and other associated
disorders. Insomnia is a worldwide disorder with different etiology which is treated with …

Plant-derived glycosides with α-glucosidase inhibitory activity: current standing and future prospects

H Khan, S Amin, D Tewari, SM Nabavi… - … Metabolic & Immune …, 2019 - ingentaconnect.com
Background: The α-glucosidase (EC 3.2. 1.20), a calcium-containing intestinal enzyme
which is positioned in the cells which cover the intestinal microvilli brush border. The …

Pharmacological basis for sedative and hypnotic like effects of Pyrus pashia using in vivo experimental models

Q Ain, H Khan - International Journal of Geriatric Psychiatry, 2019 - Wiley Online Library
Objective Pyrus pashia has traditionally been used as a therapeutic agent including
sedative. In this regard, hydroethanolic extract of Pyrus pashia (HEPP) was screened for …