Heparin, a sulfated polysaccharide belonging to the family of glycosaminoglycans, has
numerous important biological activities, associated with its interaction with diverse proteins …

Malaria is today a disease of poverty and underdeveloped countries. In Africa, mortality
remains high because there is limited access to treatment in the villages. We should follow …

Microbial surface components recognizing adhesive matrix molecules (MSCRAMMs)
comprise a group of cell surface adhesins that bind specifically to the extracellular matrix …

Immunization with attenuated Plasmodium falciparum sporozoites (PfSPZs) has been shown
to be protective against malaria, but the features of the antibody response induced by this …

Plasmodium sporozoites are deposited in the skin of their vertebrate hosts through the bite
of an infected female Anopheles mosquito. Most of these parasites find a blood vessel and …

Plasmodium sporozoites are the product of a complex developmental process in the
mosquito vector and are destined to infect the mammalian liver. Attention has been drawn to …

Plasmodium sporozoites make a remarkable journey from the mosquito midgut to the
mammalian liver. The sporozoite's major surface protein, circumsporozoite protein (CSP), is …

Many protozoans of the phylum Apicomplexa are invasive parasites that exhibit a substrate-
dependent gliding motility. Plasmodium (malaria) sporozoites, the stage of the parasite that …

Malaria is caused by protozoan parasites of the genus Plasmodium and is a major cause of
mortality and morbidity worldwide. These parasites have a complex life cycle in their …

Malaria, which is caused by Plasmodium spp., starts with an asymptomatic phase, during
which sporozoites, the parasite form that is injected into the skin by a mosquito, develop into …