Heavy metal exposure: molecular pathways, clinical implications, and protective strategies

H Koyama, T Kamogashira, T Yamasoba - Antioxidants, 2024 - mdpi.com
Heavy metals are often found in soil and can contaminate drinking water, posing a serious
threat to human health. Molecular pathways and curation therapies for mitigating heavy …

Potential protective roles of curcumin against cadmium-induced toxicity and oxidative stress

JH Park, BM Lee, HS Kim - Journal of Toxicology and …, 2021 - Taylor & Francis
Curcumin, used as a spice and traditional medicine in India, exerts beneficial effects against
several diseases, owing to its antioxidant, analgesic, and anti-inflammatory properties …

Vanillin and vanillic acid modulate antioxidant defense system via amelioration of metabolic complications linked to Fe2+-induced brain tissues damage

VF Salau, OL Erukainure, CU Ibeji… - Metabolic Brain …, 2020 - Springer
The therapeutic effect of phenolics on neurodegenerative diseases has been attributed to
their potent antioxidant properties. In the present study, the neuroprotective activities of …

Royal jelly attenuates cadmium-induced nephrotoxicity in male mice

RS Almeer, GI AlBasher, S Alarifi, S Alkahtani, D Ali… - Scientific reports, 2019 - nature.com
Cadmium exposure induces nephrotoxicity by mediating oxidative stress, inflammation, and
apoptosis. The purpose of this study was to examine the protective effect of royal jelly on Cd …

Protective Effects of Dietary Antioxidants against Vanadium‐Induced Toxicity: A Review

I Zwolak - Oxidative Medicine and Cellular Longevity, 2020 - Wiley Online Library
Vanadium (V) in its inorganic forms is a toxic metal and a potent environmental and
occupational pollutant and has been reported to induce toxic effects in animals and people …

[HTML][HTML] A comprehensive review on physiological effects of curcumin

R Ahsan, M Arshad, M Khushtar, MA Ahmad… - Drug …, 2020 - thieme-connect.com
Turmeric (Curcuma longa Linn) is an herbal medicine which is traditionally used as a spice,
food colouring or flavouring agent and widely used for several diseases such as biliary …

Curcumin administration mitigates cyclophosphamide-induced oxidative damage and restores alteration of enzymes associated with cognitive function in rats' brain

SF Akomolafe, TA Olasehinde, SI Oyeleye… - Neurotoxicity …, 2020 - Springer
The use of chemotherapeutic drugs is associated with oxidative damage, cognitive
dysfunction, and brain damage. This study sought to investigate the neuroprotective effect of …

Adenosine deaminase inhibition

S Bagheri, AA Saboury, T Haertlé - International journal of biological …, 2019 - Elsevier
Adenosine deaminase is a critical enzyme in purine metabolism that regulates intra and
extracellular adenosine concentrations by converting it to inosine. Adenosine is an important …

Syzygium aromaticum (L.) Merr. & LM Perry mitigates iron-mediated oxidative brain injury via in vitro, ex vivo, and in silico approaches

AB Ojo, GA Gyebi, O Alabi, M Iyobhebhe… - Journal of Molecular …, 2022 - Elsevier
Clove (Syzygium aromaticum) has been identified as a spice high in phytochemicals that
could be exploited in drug development. The purpose of this study is to investigate the …

Adaptogenic effects of curcumin on depression induced by moderate and unpredictable chronic stress in mice

JG da Silva Marques, FTT Antunes… - Behavioural brain …, 2021 - Elsevier
Curcumin has been investigated for the prevention and treatment of diseases due to its anti-
oxidant, anti-inflammatory, immunomodulatory, and neuroprotective actions. This current …