Cannabinoids, Phenolics, Terpenes and Alkaloids of Cannabis

MM Radwan, S Chandra, S Gul, MA ElSohly - Molecules, 2021 - mdpi.com
Cannabis sativa is one of the oldest medicinal plants in the world. It was introduced into
western medicine during the early 19th century. It contains a complex mixture of secondary …

Minor cannabinoids: Biosynthesis, molecular pharmacology and potential therapeutic uses

KB Walsh, AE McKinney, AE Holmes - Frontiers in pharmacology, 2021 - frontiersin.org
The medicinal use of Cannabis sativa L. can be traced back thousands of years to ancient
China and Egypt. While marijuana has recently shown promise in managing chronic pain …

The Medicinal Natural Products of Cannabis sativa Linn.: A Review

AE Odieka, GU Obuzor, OO Oyedeji, M Gondwe… - Molecules, 2022 - mdpi.com
Cannabis sativa is known among many cultures for its medicinal potential. Its complexity
contributes to the historical application of various parts of the plant in ethno-medicines and …

Hexahydrocannabinol and closely related semi‐synthetic cannabinoids: A comprehensive review

I Ujváry - Drug Testing and Analysis, 2024 - Wiley Online Library
Since the early 2000s, there has been a turmoil on the global illicit cannabinoid market.
Parallel to legislative changes in some jurisdictions regarding herbal cannabis, unregulated …

Cannabis sativa bioactive compounds and their extraction, separation, purification, and identification technologies: An updated review

Y Liu, HY Liu, SH Li, W Ma, DT Wu, HB Li… - TrAC Trends in …, 2022 - Elsevier
Cannabis sativa (C. sativa) has become a worldwide plant because of its multiple bioactive
compounds with a wide range of health benefits for humans. Notably, some cannabinoid …

Synthesis and pharmacological activity of the epimers of hexahydrocannabinol (HHC)

F Russo, MA Vandelli, G Biagini, M Schmid… - Scientific Reports, 2023 - nature.com
Cannabis is a multifaceted plant with numerous therapeutic properties on one hand, and
controversial psychotropic activities on the other hand, which are modulated by CB1 …

An overview on synthetic and biological activities of cannabidiol (CBD) and its derivatives

X Wang, H Zhang, Y Liu, Y Xu, B Yang, H Li… - Bioorganic Chemistry, 2023 - Elsevier
Cannabidiol is a class of non-psychoactive plant cannabinoids derived from cannabis
plants. Currently, Epidiolex (Cannabidiol) has been approved by the FDA for the treatment of …

An emerging trend in novel psychoactive substances (NPSs): designer THC

C Caprari, E Ferri, MA Vandelli, C Citti… - Journal of cannabis …, 2024 - Springer
Since its discovery as one of the main components of cannabis and its affinity towards the
cannabinoid receptor CB1, serving as a means to exert its psychoactivity, Δ9 …

Recent applications of mass spectrometry for the characterization of cannabis and hemp phytocannabinoids: from targeted to untargeted analysis

AL Capriotti, G Cannazza, M Catani, C Cavaliere… - … of Chromatography A, 2021 - Elsevier
This review is a collection of recent applications of mass spectrometry studies for the
characterization of phytocannabinoids in cannabis and hemp plant material and related …

Investigation of the intrinsic cannabinoid activity of hemp-derived and semisynthetic cannabinoids with β-arrestin2 recruitment assays—and how this matters for the …

LK Janssens, K Van Uytfanghe, JB Williams… - Archives of …, 2024 - Springer
Cultivation of industrial low-Δ9-tetrahydrocannabinol (Δ9-THC) hemp has created an
oversupply of cannabidiol (CBD)-rich products. The fact that phytocannabinoids, including …