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Advances in artificial intelligence in drug delivery and development: A comprehensive review
Artificial intelligence (AI) has emerged as a powerful tool to revolutionize the healthcare
sector, including drug delivery and development. This review explores the current and future …
sector, including drug delivery and development. This review explores the current and future …
[HTML][HTML] Artificial intelligence in pharmaceutical sciences
Drug discovery and development affects various aspects of human health and dramatically
impacts the pharmaceutical market. However, investments in a new drug often go …
impacts the pharmaceutical market. However, investments in a new drug often go …
TTD: Therapeutic Target Database describing target druggability information
Y Zhou, Y Zhang, D Zhao, X Yu, X Shen… - Nucleic acids …, 2024 - academic.oup.com
Target discovery is one of the essential steps in modern drug development, and the
identification of promising targets is fundamental for develo** first-in-class drug. A variety …
identification of promising targets is fundamental for develo** first-in-class drug. A variety …
TheMarker: a comprehensive database of therapeutic biomarkers
Y Zhang, Y Zhou, Y Zhou, X Yu, X Shen… - Nucleic Acids …, 2024 - academic.oup.com
Distinct from the traditional diagnostic/prognostic biomarker (adopted as the indicator of
disease state/process), the therapeutic biomarker (ThMAR) has emerged to be very crucial …
disease state/process), the therapeutic biomarker (ThMAR) has emerged to be very crucial …
ADCdb: the database of antibody–drug conjugates
L Shen, X Sun, Z Chen, Y Guo, Z Shen… - Nucleic Acids …, 2024 - academic.oup.com
Antibody-drug conjugates (ADCs) are a class of innovative biopharmaceutical drugs, which,
via their antibody (mAb) component, deliver and release their potent warhead (aka. payload) …
via their antibody (mAb) component, deliver and release their potent warhead (aka. payload) …
VARIDT 3.0: the phenotypic and regulatory variability of drug transporter
The phenotypic and regulatory variability of drug transporter (DT) are vital for the
understanding of drug responses, drug-drug interactions, multidrug resistances, and so on …
understanding of drug responses, drug-drug interactions, multidrug resistances, and so on …
INTEDE 2.0: the metabolic roadmap of drugs
The metabolic roadmap of drugs (MRD) is a comprehensive atlas for understanding the
stepwise and sequential metabolism of certain drug in living organisms. It plays a vital role in …
stepwise and sequential metabolism of certain drug in living organisms. It plays a vital role in …
SingPro: a knowledge base providing single-cell proteomic data
Single-cell proteomics (SCP) has emerged as a powerful tool for detecting cellular
heterogeneity, offering unprecedented insights into biological mechanisms that are masked …
heterogeneity, offering unprecedented insights into biological mechanisms that are masked …
Application of artificial intelligence in drug design: A review
Artificial intelligence (AI) is a field of computer science that involves acquiring information,
develo** rule bases, and mimicking human behaviour. The fundamental concept behind …
develo** rule bases, and mimicking human behaviour. The fundamental concept behind …
GK BertDTA: a graph representation learning and semantic embedding-based framework for drug-target affinity prediction
Develo** new drugs is costly, time-consuming, and risky. Drug-target affinity (DTA),
indicating the binding capability between drugs and target proteins, is a crucial indicator for …
indicating the binding capability between drugs and target proteins, is a crucial indicator for …