CCHFV vaccine development, current challenges, limitations, and future directions
Crimean-Congo hemorrhagic fever (CCHF) is the most prevalent tick-borne viral disease
affecting humans. The disease is life-threatening in many regions of the develo** world …
affecting humans. The disease is life-threatening in many regions of the develo** world …
Advancements and hurdles in the development of a vaccine for triple-negative breast cancer: A comprehensive review of multi-omics and immunomics strategies
Abstract Triple-Negative Breast Cancer (TNBC) presents a significant challenge in oncology
due to its aggressive behavior and limited therapeutic options. This review explores the …
due to its aggressive behavior and limited therapeutic options. This review explores the …
[HTML][HTML] A nonlinear epidemic model for tuberculosis with Caputo operator and fixed point theory
Tuberculosis (TB) is one of the most dangerous infectious diseases which spreads from one
person to another through the air and often attacks the lungs. A mathematical model of TB …
person to another through the air and often attacks the lungs. A mathematical model of TB …
Immunoinformatics-based multi-epitope vaccine design for the re-emerging monkeypox virus
Abstract Background On May 7, 2022, WHO reported a new monkeypox case. By May 2023
over 80,000 cases had been reported worldwide outside previously endemic nations.(This …
over 80,000 cases had been reported worldwide outside previously endemic nations.(This …
Development of a multi-epitope vaccine candidate for leishmanial parasites applying immunoinformatics and in vitro approaches
Leishmaniasis is a neglected tropical disease, and its severity necessitates the development
of a potent and efficient vaccine for the disease; however, no human vaccine has yet been …
of a potent and efficient vaccine for the disease; however, no human vaccine has yet been …
TgVax452, an epitope-based candidate vaccine targeting Toxoplasma gondii tachyzoite-specific SAG1-related sequence (SRS) proteins: immunoinformatics …
Background The highly expressed surface antigen 1 (SAG1)-related sequence (SRS)
proteins of T. gondii tachyzoites, as a widespread zoonotic parasite, are critical for host cell …
proteins of T. gondii tachyzoites, as a widespread zoonotic parasite, are critical for host cell …
Design, evaluation, and immune simulation of potentially universal multi-epitope mpox vaccine candidate: focus on DNA vaccine
Monkeypox (mpox) is a zoonotic infectious disease caused by the mpox virus. Mpox
symptoms are similar to smallpox with less severity and lower mortality. As yet mpox virus is …
symptoms are similar to smallpox with less severity and lower mortality. As yet mpox virus is …
Designing of a multi-epitopes based vaccine against Haemophilius parainfluenzae and its validation through integrated computational approaches
Haemophilus parainfluenzae is a Gram-negative opportunist pathogen within the mucus of
the nose and mouth without significant symptoms and has an ability to cause various …
the nose and mouth without significant symptoms and has an ability to cause various …
T cell epitope based vaccine design while targeting outer capsid proteins of rotavirus strains infecting neonates: an immunoinformatics approach
AD Sharma, RK Grewal, S Gorle… - Journal of …, 2024 - Taylor & Francis
Gastrointestinal diarrhea is majorly caused by the rotavirus (RV) in the children who
generally are under the age group of 5 years. WHO estimates that∼ 95% of the children …
generally are under the age group of 5 years. WHO estimates that∼ 95% of the children …
Reverse engineering protection: A comprehensive survey of reverse vaccinology-based vaccines targeting viral pathogens
Vaccines have significantly reduced the impact of numerous deadly viral infections.
However, there is an increasing need to expedite vaccine development in light of the …
However, there is an increasing need to expedite vaccine development in light of the …