Ethological and temporal analyses of anxiety-like behavior: the elevated plus-maze model 20 years on

AP Carobrez, LJ Bertoglio - Neuroscience & Biobehavioral Reviews, 2005 - Elsevier
As well as being considered a reliable measurement instrument of animal anxiety-like
behavior, the elevated plus-maze (EPM) is also used as a post-hoc test to evaluate …

[PDF][PDF] Neurobiology of anxiety disorders and implications for treatment.

A Garakani, SJ Mathew… - Mount Sinai Journal of …, 2006 - researchgate.net
The neurobiology of the anxiety disorders, which include panic disorder, post-traumatic
stress disorder (PTSD), and specific phobias, among others, has been clarified by advances …

Effects of test experience, closed-arm wall color, and illumination level on behavior and plasma corticosterone response in an elevated plus maze in male C57BL/6J …

H Shoji, T Miyakawa - Molecular brain, 2021 - Springer
The elevated plus maze test is a widely used test for assessing anxiety-like behavior and
screening novel therapeutic agents in rodents. Previous studies have shown that a variety of …

Pharmacodynamics of memantine: an update

CG Parsons, G Rammes… - Current …, 2008 - ingentaconnect.com
Memantine received marketing authorization from the European Agency for the Evaluation
of Medicinal Products (EMEA) for the treatment of moderately severe to severe Alzheimer's …

Three methods of behavioural testing to measure anxiety–A review

L Chen, Y Lu, X Hua, H Zhang, S Sun, C Han - Behavioural processes, 2024 - Elsevier
Behavioural test is very useful to assess the anxiety activity, screen new anxiolytic drugs,
explore the pathogenesis of anxiety disorders. Methods of behavioural testing that reflects …

Further evidence that anxiety and memory are regionally dissociated within the hippocampus

LJ Bertoglio, SRL Joca, FS Guimarães - Behavioural brain research, 2006 - Elsevier
The hippocampus has been implicated in the regulation of anxiety and memory processes.
Nevertheless, the precise contribution of its ventral (VH) and dorsal (DH) division in these …

Anxiogenic profile of AM-251, a selective cannabinoid CB1 receptor antagonist, in plus-maze-naive and plus-maze-experienced mice

RJ Rodgers, PM Evans, A Murphy - Behavioural Pharmacology, 2005 - journals.lww.com
The notoriously inconsistent effects of cannabinoids on anxiety-like behaviour may be
explained by recent research on CB1 receptor knockout (CB1-KO) mice suggesting that …

Activity in prelimbic cortex is required for adjusting the anxiety response level during the elevated plus-maze retest

CAJ Stern, FHM Do Monte, L Gazarini, AP Carobrez… - Neuroscience, 2010 - Elsevier
The prelimbic (PL) subregion of medial prefrontal cortex has been implicated in anxiety
regulation. It is unknown, however, whether PL cortex also serves to fine-tuning the level of …

Distinct ventral and dorsal hippocampus AP5 anxiolytic effects revealed in the elevated plus-maze task in rats

LPN Häckl, AP Carobrez - Neurobiology of learning and memory, 2007 - Elsevier
The hippocampal formation (HPC) mediates processes associated with learning, memory,
anxiety and fear. The glutamate N-methyl-d-aspartate (NMDA)-receptor subtype is involved …

Olfactory fear conditioning paradigm in rats: effects of midazolam, propranolol or scopolamine

JAV Kroon, AP Carobrez - Neurobiology of learning and memory, 2009 - Elsevier
In rodents, fear conditioned responses are more pronounced toward olfactory stimulus,
since olfaction is a dominant sense in these subjects. The present study was outlined to …