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Ethological and temporal analyses of anxiety-like behavior: the elevated plus-maze model 20 years on
As well as being considered a reliable measurement instrument of animal anxiety-like
behavior, the elevated plus-maze (EPM) is also used as a post-hoc test to evaluate …
behavior, the elevated plus-maze (EPM) is also used as a post-hoc test to evaluate …
[PDF][PDF] Neurobiology of anxiety disorders and implications for treatment.
A Garakani, SJ Mathew… - Mount Sinai Journal of …, 2006 - researchgate.net
The neurobiology of the anxiety disorders, which include panic disorder, post-traumatic
stress disorder (PTSD), and specific phobias, among others, has been clarified by advances …
stress disorder (PTSD), and specific phobias, among others, has been clarified by advances …
Effects of test experience, closed-arm wall color, and illumination level on behavior and plasma corticosterone response in an elevated plus maze in male C57BL/6J …
The elevated plus maze test is a widely used test for assessing anxiety-like behavior and
screening novel therapeutic agents in rodents. Previous studies have shown that a variety of …
screening novel therapeutic agents in rodents. Previous studies have shown that a variety of …
Pharmacodynamics of memantine: an update
CG Parsons, G Rammes… - Current …, 2008 - ingentaconnect.com
Memantine received marketing authorization from the European Agency for the Evaluation
of Medicinal Products (EMEA) for the treatment of moderately severe to severe Alzheimer's …
of Medicinal Products (EMEA) for the treatment of moderately severe to severe Alzheimer's …
Three methods of behavioural testing to measure anxiety–A review
L Chen, Y Lu, X Hua, H Zhang, S Sun, C Han - Behavioural processes, 2024 - Elsevier
Behavioural test is very useful to assess the anxiety activity, screen new anxiolytic drugs,
explore the pathogenesis of anxiety disorders. Methods of behavioural testing that reflects …
explore the pathogenesis of anxiety disorders. Methods of behavioural testing that reflects …
Further evidence that anxiety and memory are regionally dissociated within the hippocampus
The hippocampus has been implicated in the regulation of anxiety and memory processes.
Nevertheless, the precise contribution of its ventral (VH) and dorsal (DH) division in these …
Nevertheless, the precise contribution of its ventral (VH) and dorsal (DH) division in these …
Anxiogenic profile of AM-251, a selective cannabinoid CB1 receptor antagonist, in plus-maze-naive and plus-maze-experienced mice
The notoriously inconsistent effects of cannabinoids on anxiety-like behaviour may be
explained by recent research on CB1 receptor knockout (CB1-KO) mice suggesting that …
explained by recent research on CB1 receptor knockout (CB1-KO) mice suggesting that …
Activity in prelimbic cortex is required for adjusting the anxiety response level during the elevated plus-maze retest
The prelimbic (PL) subregion of medial prefrontal cortex has been implicated in anxiety
regulation. It is unknown, however, whether PL cortex also serves to fine-tuning the level of …
regulation. It is unknown, however, whether PL cortex also serves to fine-tuning the level of …
Distinct ventral and dorsal hippocampus AP5 anxiolytic effects revealed in the elevated plus-maze task in rats
LPN Häckl, AP Carobrez - Neurobiology of learning and memory, 2007 - Elsevier
The hippocampal formation (HPC) mediates processes associated with learning, memory,
anxiety and fear. The glutamate N-methyl-d-aspartate (NMDA)-receptor subtype is involved …
anxiety and fear. The glutamate N-methyl-d-aspartate (NMDA)-receptor subtype is involved …
Olfactory fear conditioning paradigm in rats: effects of midazolam, propranolol or scopolamine
JAV Kroon, AP Carobrez - Neurobiology of learning and memory, 2009 - Elsevier
In rodents, fear conditioned responses are more pronounced toward olfactory stimulus,
since olfaction is a dominant sense in these subjects. The present study was outlined to …
since olfaction is a dominant sense in these subjects. The present study was outlined to …