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The diversified role of mitochondria in ferroptosis in cancer
Ferroptosis is a form of regulated cell death induced by iron-dependent lipid peroxidation,
and it has been studied extensively since its discovery in 2012. Induced by iron overload …
and it has been studied extensively since its discovery in 2012. Induced by iron overload …
Mitochondria-targeted BODIPY dyes for small molecule recognition, bio-imaging and photodynamic therapy
Mitochondria are essential for a diverse array of biological functions. There is increasing
research focus on develo** efficient tools for mitochondria-targeted detection and …
research focus on develo** efficient tools for mitochondria-targeted detection and …
Glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis
M Tan, Y Yin, X Ma, J Zhang, W Pan, M Tan… - Cell Death & …, 2023 - nature.com
The glutathione (GSH) system is considered to be one of the most powerful endogenous
antioxidant systems in the cardiovascular system due to its key contribution to detoxifying …
antioxidant systems in the cardiovascular system due to its key contribution to detoxifying …
[HTML][HTML] Oxidative stress–Complex pathological issues concerning the hallmark of cardiovascular and metabolic disorders
Oxidative stress is a complex biological process characterized by the excessive production
of reactive oxygen species (ROS) that act as destroyers of the REDOX balance in the body …
of reactive oxygen species (ROS) that act as destroyers of the REDOX balance in the body …
Mitochondrial dysfunction and oxidative stress in heart disease
Beyond their role as a cellular powerhouse, mitochondria are emerging as integral players
in molecular signaling and cell fate determination through reactive oxygen species (ROS) …
in molecular signaling and cell fate determination through reactive oxygen species (ROS) …
ROS generation and antioxidant defense systems in normal and malignant cells
AV Snezhkina, AV Kudryavtseva… - Oxidative medicine …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) are by‐products of normal cell activity. They are produced
in many cellular compartments and play a major role in signaling pathways. Overproduction …
in many cellular compartments and play a major role in signaling pathways. Overproduction …
Structural features of small molecule antioxidants and strategic modifications to improve potential bioactivity
This review surveys the major structural features in various groups of small molecules that
are considered to be antioxidants, including natural and synthetic compounds alike. Recent …
are considered to be antioxidants, including natural and synthetic compounds alike. Recent …
Nutritional significance of amino acids, vitamins and minerals as nutraceuticals in poultry production and health–a comprehensive review
Nutraceuticals have gained immense importance in poultry science recently considering the
nutritional and beneficial health effects of their constituents. Besides providing nutritional …
nutritional and beneficial health effects of their constituents. Besides providing nutritional …
Mitochondrial glutathione in cellular redox homeostasis and disease manifestation
TH Chen, HC Wang, CJ Chang, SY Lee - International Journal of …, 2024 - mdpi.com
Mitochondria are critical for providing energy to maintain cell viability. Oxidative
phosphorylation involves the transfer of electrons from energy substrates to oxygen to …
phosphorylation involves the transfer of electrons from energy substrates to oxygen to …
Glutathione in brain disorders and aging
Glutathione is a remarkably functional molecule with diverse features, which include being
an antioxidant, a regulator of DNA synthesis and repair, a protector of thiol groups in …
an antioxidant, a regulator of DNA synthesis and repair, a protector of thiol groups in …