Repurposing drugs by uncovering new indications for approved drugs accelerates the
process of establishing new treatments and reduces the high costs of drug discovery and …

Lung cancer is the most common type of cancer, with over 2.1 million cases diagnosed
annually worldwide. It has a high incidence and mortality rate, leading to extensive research …

Lung cancer is managed using conventional therapies, including chemotherapy, radiation
therapy, or a combination of both. Each of these therapies has its own limitations, such as …

Lung cancer is one of the leading causes of death worldwide, whereby the major
contributing factors are cigarette smoking and exposure to environmental pollutants. Despite …

Cancer is a highly complex disease characterized by genetic and phenotypic heterogeneity
among individuals. In the era of precision medicine, understanding the genetic basis of …

Purpose: The expression and regulatory mechanism of NSUN6 in lung cancer are still
unclear. Our study explored whether NSUN6 mediates progression of lung cancer by …

The coamorphous systems (CAM) of lumefantrine (LMF) and alpha-ketoglutaric acid (KGA)
were developed using three different methods to address the solubility and bioavailability …

Non-small cell lung cancer (NSCLC) is a type of lung cancer associated with translocation of
the EML4 and ALK genes on the short arm of chromosome 2. This leads to the development …

Abstract Targeted gemcitabine (GEB) loaded 5-N-acetyl-neuraminic acid (Neu5Ac)
assembled chitosan nanoparticles (CA-NPs) were formulated by ionotropic gelation process …

Repurposing existing drugs appears to be a potential solution for addressing the challenges
in the treatment of non-small cell lung cancer (NSCLC). β-adrenoceptor antagonist drugs (β …