Methylation of structured RNA by the m6A writer METTL16 is essential for mouse embryonic development
Internal modification of RNAs with N 6-methyladenosine (m 6 A) is a highly conserved
means of gene expression control. While the METTL3/METTL14 heterodimer adds this mark …
means of gene expression control. While the METTL3/METTL14 heterodimer adds this mark …
mScarlet3: a brilliant and fast-maturing red fluorescent protein
TWJ Gadella Jr, L van Weeren, J Stouthamer… - Nature …, 2023 - nature.com
We report the evolution of mScarlet3, a cysteine-free monomeric red fluorescent protein with
fast and complete maturation, as well as record brightness, quantum yield (75%) and …
fast and complete maturation, as well as record brightness, quantum yield (75%) and …
An allosteric redox switch involved in oxygen protection in a CO2 reductase
Metal-dependent formate dehydrogenases reduce CO2 with high efficiency and selectivity,
but are usually very oxygen sensitive. An exception is Desulfovibrio vulgaris W/Sec-FdhAB …
but are usually very oxygen sensitive. An exception is Desulfovibrio vulgaris W/Sec-FdhAB …
Structural polymorphisms within a common powdery mildew effector scaffold as a driver of coevolution with cereal immune receptors
In plants, host–pathogen coevolution often manifests in reciprocal, adaptive genetic
changes through variations in host nucleotide-binding leucine-rich repeat immune receptors …
changes through variations in host nucleotide-binding leucine-rich repeat immune receptors …
A molecular mechanism for transthyretin amyloidogenesis
Human transthyretin (TTR) is implicated in several fatal forms of amyloidosis. Many
mutations of TTR have been identified; most of these are pathogenic, but some offer …
mutations of TTR have been identified; most of these are pathogenic, but some offer …
Accurate and rapid 3D printing of microfluidic devices using wavelength selection on a DLP printer
PJEM van der Linden, AM Popov, D Pontoni - Lab on a Chip, 2020 - pubs.rsc.org
The use of microfluidics on synchrotron X-ray beamlines represents an advanced sample
preparation and delivery platform for state-of-the-art X-ray characterization of micro-samples …
preparation and delivery platform for state-of-the-art X-ray characterization of micro-samples …
Iron–sulfur clusters toward stresses: implication for understanding and fighting tuberculosis
I Elchennawi, S Ollagnier de Choudens - Inorganics, 2022 - mdpi.com
Tuberculosis (TB) remains the leading cause of death due to a single pathogen, accounting
for 1.5 million deaths annually on the global level. Mycobacterium tuberculosis, the …
for 1.5 million deaths annually on the global level. Mycobacterium tuberculosis, the …
Toward the Mechanistic Understanding of Enzymatic CO2 Reduction
Reducing CO2 is a challenging chemical transformation that biology solves easily, with high
efficiency and specificity. In particular, formate dehydrogenases are of great interest since …
efficiency and specificity. In particular, formate dehydrogenases are of great interest since …
The CTPase activity of ParB determines the size and dynamics of prokaryotic DNA partition complexes
ParB-like CTPases mediate the segregation of bacterial chromosomes and low-copy
number plasmids. They act as DNA-sliding clamps that are loaded at parS motifs in the …
number plasmids. They act as DNA-sliding clamps that are loaded at parS motifs in the …
Aequorea's secrets revealed: New fluorescent proteins with unique properties for bioimaging and biosensing
Using mRNA sequencing and de novo transcriptome assembly, we identified, cloned, and
characterized 9 previously undiscovered fluorescent protein (FP) homologs from Aequorea …
characterized 9 previously undiscovered fluorescent protein (FP) homologs from Aequorea …