A practical guide to environmental association analysis in landscape genomics
Landscape genomics is an emerging research field that aims to identify the environmental
factors that shape adaptive genetic variation and the gene variants that drive local …
factors that shape adaptive genetic variation and the gene variants that drive local …
Sequencing pools of individuals—mining genome-wide polymorphism data without big funding
The analysis of polymorphism data is becoming increasingly important as a complementary
tool to classical genetic analyses. Nevertheless, despite plunging sequencing costs …
tool to classical genetic analyses. Nevertheless, despite plunging sequencing costs …
LEA: An R package for landscape and ecological association studies
Based on population genomic and environmental data, genomewide ecological association
studies aim at detecting allele frequencies that exhibit significant statistical association with …
studies aim at detecting allele frequencies that exhibit significant statistical association with …
Genome-wide scan for adaptive divergence and association with population-specific covariates
M Gautier - Genetics, 2015 - academic.oup.com
In population genomics studies, accounting for the neutral covariance structure across
population allele frequencies is critical to improve the robustness of genome-wide scan …
population allele frequencies is critical to improve the robustness of genome-wide scan …
Detecting natural selection in genomic data
The past fifty years have seen the development and application of numerous statistical
methods to identify genomic regions that appear to be shaped by natural selection. These …
methods to identify genomic regions that appear to be shaped by natural selection. These …
Robust identification of local adaptation from allele frequencies
Comparing allele frequencies among populations that differ in environment has long been a
tool for detecting loci involved in local adaptation. However, such analyses are complicated …
tool for detecting loci involved in local adaptation. However, such analyses are complicated …
Testing for associations between loci and environmental gradients using latent factor mixed models
Adaptation to local environments often occurs through natural selection acting on a large
number of loci, each having a weak phenotypic effect. One way to detect these loci is to …
number of loci, each having a weak phenotypic effect. One way to detect these loci is to …
How culture shaped the human genome: bringing genetics and the human sciences together
Researchers from diverse backgrounds are converging on the view that human evolution
has been shaped by gene–culture interactions. Theoretical biologists have used population …
has been shaped by gene–culture interactions. Theoretical biologists have used population …
The genetics of human adaptation: hard sweeps, soft sweeps, and polygenic adaptation
There has long been interest in understanding the genetic basis of human adaptation. To
what extent are phenotypic differences among human populations driven by natural …
what extent are phenotypic differences among human populations driven by natural …
Signatures of environmental genetic adaptation pinpoint pathogens as the main selective pressure through human evolution
Previous genome-wide scans of positive natural selection in humans have identified a
number of non-neutrally evolving genes that play important roles in skin pigmentation …
number of non-neutrally evolving genes that play important roles in skin pigmentation …