Peripheral neuropathy is one of the most common complications of both type 1 and type 2
diabetes. Up to half of patients with diabetes develop neuropathy during the course of their …

The incidence of both type 1 and type 2 diabetes is increasing worldwide. Diabetic
peripheral neuropathy (DPN) is among the most distressing and costly of all the chronic …

Small fibre neuropathies are a heterogeneous group of disorders affecting thinly myelinated
Aδ-fibres and unmyelinated C-fibres. Although multiple causes of small nerve fibre …

Diabetic neuropathy, with its major clinical sequels, notably neuropathic pain, foot ulcers,
and autonomic dysfunction, is associated with substantial morbidity, increased risk of …

Objectives Corneal confocal microscopy (CCM) is a rapid, non-invasive, reproducible
technique that quantifies small nerve fibres. We have compared the diagnostic capability of …

Abstract The World Health Organization regards chronic pain to be a public health concern.
In clinical medicine, fibromyalgia (FM) is the most prevalent chronic widespread pain …

There are potentially many ways of assessing diabetic peripheral neuropathy (DPN).
However, they do not fulfill US Food and Drug Administration (FDA) requirements in relation …

Diabetic peripheral neuropathy (DPN) is the most common complication of both type 1 and 2
diabetes. As a result, neuropathic pain, diabetic foot ulcers and lower-limb amputations …

Aims/hypothesis Small cohort studies raise the hypothesis that corneal nerve abnormalities
(including corneal nerve fibre length [CNFL]) are valid non-invasive imaging endpoints for …

Aims/hypothesis We aimed to develop an artificial intelligence (AI)-based deep learning
algorithm (DLA) applying attribution methods without image segmentation to corneal …