We propose a new conceptual framework (computational validity) for translation across
species and populations based on the computational similarity between the information …

One of the great challenges of systems neuroscience is to understand how the neocortex
transforms neuronal representations of the physical characteristics of sensory stimuli into the …

Many theories of brain function propose that activity in sparse subsets of neurons underlies
perception and action. To place a lower bound on the amount of neural activity that can be …

For many of our senses, the role of the cerebral cortex in detecting stimuli is
controversial,,,,,,,,,,,,,,,–. Here we examine the effects of both acute and chronic inactivation of …

The location of short-term memory in mammalian neocortex remains elusive. Here we show
that distinct neocortical areas maintain short-term memory depending on behavioral …

When a neuron responds to a sensory stimulus, two fundamental codes [1–6] may transmit
the information specifying stimulus identity—spike rate (the total number of spikes in the …

A key question in systems neuroscience is to identify how sensory stimuli are represented in
neuronal activity, and how the activity of sensory neurons in turn is “read out” by downstream …

A fundamental question of current ecological research concerns the drives and limits of
species responses to human-induced rapid environmental change (HIREC). Behavioural …

Here, we reconsider the status quo in testing mechanical sensitivity with von Frey's hairs.
The aim is to improve paw withdrawal estimates by integrating current psychometric theory …

Understanding how populations of neurons encode information is the challenge faced by
researchers in the field of neural coding. Focusing on the many mysteries and marvels of the …