Hyperthermophilic enzymes: sources, uses, and molecular mechanisms for thermostability

C Vieille, GJ Zeikus - Microbiology and molecular biology reviews, 2001 - Am Soc Microbiol
Enzymes synthesized by hyperthermophiles (bacteria and archaea with optimal growth
temperatures of> 80° C), also called hyperthermophilic enzymes, are typically thermostable …

Metal and redox modulation of cysteine protein function

NM Giles, AB Watts, GI Giles, FH Fry, JA Littlechild… - Chemistry & biology, 2003 - cell.com
In biological systems, the amino acid cysteine combines catalytic activity with an extensive
redox chemistry and unique metal binding properties. The interdependency of these three …

Use of TLS parameters to model anisotropic displacements in macromolecular refinement

MD Winn, MN Isupov, GN Murshudov - … Section D: Biological …, 2001 - journals.iucr.org
An essential step in macromolecular refinement is the selection of model parameters which
give as good a description of the experimental data as possible while retaining a realistic …

Macromolecular TLS refinement in REFMAC at moderate resolutions

MD Winn, GN Murshudov, MZ Papiz - Methods in enzymology, 2003 - Elsevier
Publisher Summary This chapter discusses the translation, rotation, and screw-rotation
(TLS) parameterization of anisotropic displacement parameters (ADPs). In general, each …

Carbohydrate metabolism in Archaea: current insights into unusual enzymes and pathways and their regulation

C Bräsen, D Esser, B Rauch… - … and Molecular Biology …, 2014 - Am Soc Microbiol
The metabolism of Archaea, the third domain of life, resembles in its complexity those of
Bacteria and lower Eukarya. However, this metabolic complexity in Archaea is accompanied …

Template-assisted filament growth by parallel stacking of tau

M Margittai, R Langen - Proceedings of the National …, 2004 - National Acad Sciences
Tau Filaments are found in> 20 neurodegenerative diseases. Yet, because of their
enormous molecular weights and poor tendency to form highly ordered 3D crystal lattices …

[HTML][HTML] The architecture of parallel β-helices and related folds

J Jenkins, R Pickersgill - Progress in biophysics and molecular biology, 2001 - Elsevier
Three-dimensional structures have been determined of a large number of proteins
characterized by a repetitive fold where each of the repeats (coils) supplies a strand to one …

Unusual pathways and enzymes of central carbohydrate metabolism in Archaea

B Siebers, P Schönheit - Current opinion in microbiology, 2005 - Elsevier
Sugar-utilizing hyperthermophilic and halophilic Archaea degrade glucose and glucose
polymers to acetate or to CO2 using O2, nitrate, sulfur or sulfate as electron acceptors …

Posttranslational Protein Modification in Archaea

J Eichler, MWW Adams - Microbiology and Molecular Biology …, 2005 - Am Soc Microbiol
One of the first hurdles to be negotiated in the postgenomic era involves the description of
the entire protein content of the cell, the proteome. Such efforts are presently complicated by …

Growth media in anaerobic fermentative processes: The underestimated potential of thermophilic fermentation and anaerobic digestion

A Hendriks, JB Van Lier, MK De Kreuk - Biotechnology Advances, 2018 - Elsevier
Fermentation and anaerobic digestion of organic waste and wastewater is broadly studied
and applied. Despite widely available results and data for these processes, comparison of …