New insights into the circadian rhythm and its related diseases

Y **e, Q Tang, G Chen, M **e, S Yu, J Zhao… - Frontiers in …, 2019 - frontiersin.org
Circadian rhythms (CR) are a series of endogenous autonomous oscillators generated by
the molecular circadian clock which acting on coordinating internal time with the external …

Physiology of circadian entrainment

DA Golombek, RE Rosenstein - Physiological reviews, 2010 - journals.physiology.org
Mammalian circadian rhythms are controlled by endogenous biological oscillators, including
a master clock located in the hypothalamic suprachiasmatic nuclei (SCN). Since the period …

Light and cognition: roles for circadian rhythms, sleep, and arousal

AS Fisk, SKE Tam, LA Brown, VV Vyazovskiy… - Frontiers in …, 2018 - frontiersin.org
Light exerts a wide range of effects on mammalian physiology and behavior. As well as
synchronizing circadian rhythms to the external environment, light has been shown to …

Suprachiasmatic nucleus: cell autonomy and network properties

DK Welsh, JS Takahashi, SA Kay - Annual review of physiology, 2010 - annualreviews.org
The suprachiasmatic nucleus (SCN) is the primary circadian pacemaker in mammals.
Individual SCN neurons in dispersed culture can generate independent circadian …

Linking neural activity and molecular oscillations in the SCN

CS Colwell - Nature Reviews Neuroscience, 2011 - nature.com
Neurons in the suprachiasmatic nucleus (SCN) function as part of a central timing circuit that
drives daily changes in our behaviour and underlying physiology. A hallmark feature of SCN …

Photic entrainment of the circadian system

A Ashton, RG Foster, A Jagannath - International journal of molecular …, 2022 - mdpi.com
Circadian rhythms are essential for the survival of all organisms, enabling them to predict
daily changes in the environment and time their behaviour appropriately. The molecular …

Clock-talk: interactions between central and peripheral circadian oscillators in mammals

U Schibler, I Gotic, C Saini, P Gos… - Cold Spring Harbor …, 2015 - symposium.cshlp.org
In mammals, including humans, nearly all physiological processes are subject to daily
oscillations that are governed by a circadian timing system with a complex hierarchical …

Interactions of the circadian CLOCK system and the HPA axis

N Nader, GP Chrousos, T Kino - Trends in Endocrinology & Metabolism, 2010 - cell.com
Organisms have developed concurrent behavioral and physiological adaptations to the
strong influence of day/night cycles, as well as to unforeseen, random stress stimuli. These …

The art of entrainment

T Roenneberg, S Daan… - Journal of biological …, 2003 - journals.sagepub.com
The circadian system actively synchronizes the temporal sequence of biological functions
with the environment. The oscillatory behavior of the system ensures that entrainment is not …

Replication of cortisol circadian rhythm: new advances in hydrocortisone replacement therapy

S Chan, M Debono - Therapeutic advances in endocrinology …, 2010 - journals.sagepub.com
Cortisol has one of the most distinct and fascinating circadian rhythms in human physiology.
This is regulated by the central clock located in the suprachiasmatic nucleus of the …