Virus infections and autoimmune disease have long been linked. These infections often
precede the occurrence of inflammation in the target organ. Several mechanisms often used …

Myocarditis is the inflammation of the muscle tissues of the heart (myocardium). After a
pathologic cardiac-specific inflammatory process, it may progress to chronic damage and …

Enteroviruses such as Coxsackievirus B3 can cause dilated cardiomyopathy, but the
mechanism of this pathology is unknown. Mutations in cytoskeletal proteins such as …

Background—Viral infections are important causes of myocarditis and may induce cardiac
dysfunction and finally lead to dilated cardiomyopathy. We investigated whether interferon …

Acute pericarditis is often accompanied by some degree of myocarditis. In clinical practice
both pericarditis and myocarditis coexist because they share common etiologic agents …

Viral infection of the heart is relatively common and usually of little consequence. It can,
however, lead to substantial cardiac damage and severe acute heart failure. It can also …

ABSTRACT Coxsackievirus B3 (CVB3) is the most common human pathogen for viral
myocarditis. We have previously shown that the signaling protein p21 ras GTPase-activating …

Enteroviral infection of the heart has been noted in a significant proportion of cases of
myocarditis and dilated cardiomyopathy. The presence of enterovirus RNA at stages of …

Enteroviral persistence has been implicated in the pathogenesis of several chronic human
diseases, including dilated cardiomyopathy, insulin-dependent diabetes mellitus, and …

Aims Human immunodeficiency virus infection (HIV) has been associated with cardiac
dysfunction that, if present, can negatively affect morbidity and mortality of HIV-infected …