Metabolic engineering of the shikimate pathway for production of aromatics and derived compounds—present and future strain construction strategies

NJH Averesch, JO Krömer - Frontiers in Bioengineering and …, 2018 - frontiersin.org
The aromatic nature of shikimate pathway intermediates gives rise to a wealth of potential
bio-replacements for commonly fossil fuel-derived aromatics, as well as naturally produced …

Harnessing yeast metabolism of aromatic amino acids for fermented beverage bioflavouring and bioproduction

AG Cordente, S Schmidt, G Beltran, MJ Torija… - Applied Microbiology …, 2019 - Springer
Aromatic amino acid metabolism in yeast is an important source of secondary compounds
that influence the aroma and flavour of alcoholic beverages and foods. Examples are the …

Rational engineering of Kluyveromyces marxianus to create a chassis for the production of aromatic products

AS Rajkumar, JP Morrissey - Microbial Cell Factories, 2020 - Springer
Abstract Background The yeast Kluyveromyces marxianus offers unique potential for
industrial biotechnology because of useful features like rapid growth, thermotolerance and a …

Metabolic Engineering of Pseudomonas putida KT2440 for the Production of para-Hydroxy Benzoic Acid

S Yu, MR Plan, G Winter, JO Krömer - Frontiers in bioengineering and …, 2016 - frontiersin.org
para-Hydroxy benzoic acid (PHBA) is the key component for preparing parabens, a common
preservatives in food, drugs, and personal care products, as well as high-performance …

Metabolomics tools for the synthetic biology of natural products

KA Hollywood, K Schmidt, E Takano… - Current Opinion in …, 2018 - Elsevier
Metabolomics plays an increasingly central role within the Design–Build–Test cycle of
synthetic biology, in particular in applications targeting the discovery, diversification and …

Bioprocess optimization for the production of aromatic compounds with metabolically engineered hosts: recent developments and future challenges

A Braga, N Faria - Frontiers in bioengineering and biotechnology, 2020 - frontiersin.org
The most common route to produce aromatic chemicals–organic compounds containing at
least one benzene ring in their structure–is chemical synthesis. These processes, usually …

Systems metabolic engineering of Escherichia coli for high-yield production of Para-hydroxybenzoic acid

Q Liu, X Chen, G Hu, R Chu, J Liu, X Li, C Gao, L Liu… - Food Chemistry, 2024 - Elsevier
Para-hydroxybenzoic acid (PHBA) is extensively used as an additive in the food and
cosmetics industries, significantly enhancing product shelf life and stability. While microbial …

Enhanced production of para-hydroxybenzoic acid by genetically engineered Saccharomyces cerevisiae

NJH Averesch, A Prima, JO Krömer - Bioprocess and Biosystems …, 2017 - Springer
Saccharomyces cerevisiae is a popular organism for metabolic engineering; however,
studies aiming at over-production of bio-replacement precursors for the chemical industry …

Agromyces laixinhei sp. nov. isolated from bat feces in China

Y Cheng, Y Bai, Y Huang, J Yang, S Lu, D **… - Journal of …, 2021 - Springer
Three rod-shaped, Gram-stain-positive, and catalase-positive, phenotypically closely related
isolates (HY052 T, HY050, and HY045) were obtained from fecal samples collected from …

[KNYGA][B] Analysis of genetic and physiological determinants involved in the production of aromatic amino acid derived compounds (AADC) in Saccharomyces …

RB Alcaraz, JMG Navarro - 2023 - roderic.uv.es
INFORMA: Que Ricardo Bisquert Alcaraz, graduado en Biología por la Universidad de
Valencia, ha realizado bajo mi dirección el trabajo de Tesis Doctoral que lleva por título …