Roles of intestinal Parabacteroides in human health and diseases
The stability of gut microbiota is essential for the host's health. Parabacteroides spp., core
members of the human gut microbiota, have an average abundance of 1.27% in humans of …
members of the human gut microbiota, have an average abundance of 1.27% in humans of …
A journey from structure to function of bacterial lipopolysaccharides
Lipopolysaccharide (LPS) is a crucial constituent of the outer membrane of most Gram-
negative bacteria, playing a fundamental role in the protection of bacteria from …
negative bacteria, playing a fundamental role in the protection of bacteria from …
[HTML][HTML] High-fat diet promotes colorectal tumorigenesis through modulating gut microbiota and metabolites
Background and Aims Dietary fat intake is associated with increased risk of colorectal
cancer (CRC). We examined the role of high-fat diet (HFD) in driving CRC through …
cancer (CRC). We examined the role of high-fat diet (HFD) in driving CRC through …
Parabacteroides distasonis alleviates obesity and metabolic dysfunctions via production of succinate and secondary bile acids
We demonstrated the metabolic benefits of Parabacteroides distasonis (PD) on decreasing
weight gain, hyperglycemia, and hepatic steatosis in ob/ob and high-fat diet (HFD)-fed mice …
weight gain, hyperglycemia, and hepatic steatosis in ob/ob and high-fat diet (HFD)-fed mice …
Integrated analysis of the faecal metagenome and serum metabolome reveals the role of gut microbiome-associated metabolites in the detection of colorectal cancer …
Objective To profile gut microbiome-associated metabolites in serum and investigate
whether these metabolites could distinguish individuals with colorectal cancer (CRC) or …
whether these metabolites could distinguish individuals with colorectal cancer (CRC) or …
Parabacteroides distasonis: intriguing aerotolerant gut anaerobe with emerging antimicrobial resistance and pathogenic and probiotic roles in human health
JC Ezeji, DK Sarikonda, A Hopperton, HL Erkkila… - Gut …, 2021 - Taylor & Francis
Parabacteroides distasonis is the type strain for the genus Parabacteroides, a group of gram-
negative anaerobic bacteria that commonly colonize the gastrointestinal tract of numerous …
negative anaerobic bacteria that commonly colonize the gastrointestinal tract of numerous …
Parabacteroides produces acetate to alleviate heparanase-exacerbated acute pancreatitis through reducing neutrophil infiltration
Y Lei, L Tang, S Liu, S Hu, L Wu, Y Liu, M Yang… - Microbiome, 2021 - Springer
Background The endoglycosidase heparanase which degrades heparan sulfate
proteoglycans, exerts a pro-inflammatory mediator in various inflammatory disorders …
proteoglycans, exerts a pro-inflammatory mediator in various inflammatory disorders …
Parabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a
Y Sun, Q Nie, S Zhang, H He, S Zuo, C Chen… - Nature …, 2023 - nature.com
Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control
study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis …
study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis …
How diet and physical activity modulate gut microbiota: evidence, and perspectives
D Campaniello, MR Corbo, M Sinigaglia, B Speranza… - Nutrients, 2022 - mdpi.com
Gut microbiota plays a significant role in the maintenance of physiological homeostasis,
contributing to human health. Nevertheless, some factors (sex, age, lifestyle, physical …
contributing to human health. Nevertheless, some factors (sex, age, lifestyle, physical …
Precision nutrition and the microbiome, part I: current state of the science
The gut microbiota is a highly complex community which evolves and adapts to its host over
a lifetime. It has been described as a virtual organ owing to the myriad of functions it …
a lifetime. It has been described as a virtual organ owing to the myriad of functions it …