Ribonuclease inhibitor: structure and function
KA Dickson, MC Haigis, RT Raines - Progress in nucleic acid research and …, 2005 - Elsevier
Publisher Summary The mammalian ribonuclease inhibitor (RI) is a 50‐kDa cytosolic protein
that binds to pancreatic‐type ribonucleases with femtomolar affinity and renders them …
that binds to pancreatic‐type ribonucleases with femtomolar affinity and renders them …
Oligomer formation by 3D domain swap**: a model for protein assembly and misassembly
MP Schlunegger, MJ Bennett, D Eisenberg - Advances in protein chemistry, 1997 - Elsevier
Publisher Summary This chapter examines one type of interchain, noncovalent protein-
protein bond: 3D domain swap**. To date, 3D domain swap** has been definitively …
protein bond: 3D domain swap**. To date, 3D domain swap** has been definitively …
[BOOK][B] The enzymes
PD Boyer, EG Krebs - 1986 - books.google.com
The enzymes Page 1 |||| ENAMES THIRD EDITION Edited by Paul D. Boyer Edwin G. Krebs
VOLUME XVI Control by Phosphorylation, Part A. General Features Specific Enzymes []) Page 2 …
VOLUME XVI Control by Phosphorylation, Part A. General Features Specific Enzymes []) Page 2 …
Identification of a structural glycoprotein of an RNA virus as a ribonuclease
R Schneider, G Unger, R Stark, E Schneider-Scherzer… - Science, 1993 - science.org
One of the three structural glycoproteins of classical swine fever virus (CSFV) is E0, a
disulfide-bonded homodimer that induces virus-neutralizing antibodies and occurs in a …
disulfide-bonded homodimer that induces virus-neutralizing antibodies and occurs in a …
Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicity
TJ Rutkoski, RT Raines - Current pharmaceutical …, 2008 - ingentaconnect.com
Onconase®(ONC) is an amphibian member of the bovine pancreatic ribonuclease (RNase
A) superfamily that exhibits innate antitumoral activity. ONC has been granted both orphan …
A) superfamily that exhibits innate antitumoral activity. ONC has been granted both orphan …
Binase and other microbial RNases as potential anticancer agents
AA Makarov, A Kolchinsky, ON Ilinskaya - BioEssays, 2008 - Wiley Online Library
Some RNases possess preferential cytotoxicity against malignant cells. The best known of
these RNases, onconase, was isolated from frog oocytes and is in clinical trials as …
these RNases, onconase, was isolated from frog oocytes and is in clinical trials as …
Molecular evolution of the ribonuclease superfamily
JJ Beintema, C Schüller, M Irie, A Carsana - Progress in biophysics and …, 1988 - Elsevier
The genome of multi-cellular eukaryotic organisms contains both structural genes expressed
in all cells and genes that are expressed in specialized tissues only. However, a clear …
in all cells and genes that are expressed in specialized tissues only. However, a clear …
12 Pancreatic Ribonuclease
P Blackburn, S Moore - The enzymes, 1982 - Elsevier
Publisher Summary Bovine Ribonuclease has been a test protein in the study of a wide
variety of chemical and physical methods of protein chemistry. It is widely employed in the …
variety of chemical and physical methods of protein chemistry. It is widely employed in the …
Seminal RNase: a unique member of the ribonuclease superfamily
G D'Alessio, A Di Donato, A Parente… - Trends in biochemical …, 1991 - cell.com
BS-RNase is the only known dimeric protein in the ribonuclease superfamily. It also presents
a rare feature for a small oligomeric enzyme: non-covalent interactions and two intersubunit …
a rare feature for a small oligomeric enzyme: non-covalent interactions and two intersubunit …
Ribonucleases and their antitumor activity
J Matoušek - Comparative Biochemistry and Physiology Part C …, 2001 - Elsevier
The antitumor effect of ribonucleases was studied with animal ribonucleolytic enzymes,
bovine pancreatic RNase A, bovine seminal RNase (BS-RNase), onconase and angiogenin …
bovine pancreatic RNase A, bovine seminal RNase (BS-RNase), onconase and angiogenin …