Galectins are animal lectins with specific affinity for galactosides via the conserved
carbohydrate recognition domains. Increasing studies recently have identified critical roles …

Autophagy is a vital physiological process that maintains intracellular homeostasis by
removing damaged organelles and senescent or misfolded molecules. However, excessive …

Galectin-3 (Gal-3) plays a multifaceted role in the development, progression, and prognosis
of pancreatic ductal adenocarcinoma (PDAC). This review offers a comprehensive …

Macroautophagy/autophagy is an intracellular degradation pathway that has an important
effect on both healthy and diseased pancreases. It protects the structure and function of the …

In solid tumors, the development of vasculature is, to some extent, slower than the
proliferation of the different types of cells that form the tissue, both cancer and stroma cells …

The structural and associated molecules of the extracellular matrix (ECM) complex is an
important component of the local milieu of cells, both for maintaining their functions and …

Autophagy is a highly conserved recycling process carried out ubiquitously in humans that
primarily involves both selective and non-selective degradation of cellular materials ranging …