Preeclampsia beyond pregnancy: long-term consequences for mother and child

HR Turbeville, JM Sasser - American Journal of Physiology …, 2020 - journals.physiology.org
Preeclampsia is defined as new-onset hypertension after the 20th wk of gestation along with
evidence of maternal organ failure. Rates of preeclampsia have steadily increased over the …

[HTML][HTML] Pathogenesis of preeclampsia and therapeutic approaches targeting the placenta

MK Jena, NR Sharma, M Petitt, D Maulik, NR Nayak - Biomolecules, 2020 - mdpi.com
Preeclampsia (PE) is a serious pregnancy complication, affecting about 5–7% of
pregnancies worldwide and is characterized by hypertension and damage to multiple …

The programming power of the placenta

AN Sferruzzi-Perri, EJ Camm - Frontiers in physiology, 2016 - frontiersin.org
Size at birth is a critical determinant of life expectancy, and is dependent primarily on the
placental supply of nutrients. However, the placenta is not just a passive organ for the …

Animal models of preeclampsia: causes, consequences, and interventions

KL Gatford, PH Andraweera, CT Roberts, AS Care - Hypertension, 2020 - ahajournals.org
Preeclampsia is a common pregnancy complication, affecting 2% to 8% of pregnancies
worldwide, and is an important cause of both maternal and fetal morbidity and mortality …

Preeclampsia link to gestational hypoxia

W Tong, DA Giussani - Journal of developmental origins of health …, 2019 - cambridge.org
Complications of pregnancy remain key drivers of morbidity and mortality, affecting the
health of both the mother and her offspring in the short and long term. There is lack of …

Placental growth factor administration abolishes placental ischemia-induced hypertension

FT Spradley, AY Tan, WS Joo, G Daniels, P Kussie… - …, 2016 - ahajournals.org
Preeclampsia is a pregnancy-specific disorder of new-onset hypertension. Unfortunately, the
most effective treatment is early delivery of the fetus and placenta. Placental ischemia …

The complement system and preeclampsia

JF Regal, RM Burwick, SD Fleming - Current hypertension reports, 2017 - Springer
Abstract Purpose of Review Preeclampsia affects 3–4% of pregnancies with few treatment
options to reduce maternal and fetal harm. Recent evidence that targeting the complement …

Preeclampsia: linking placental ischemia with maternal endothelial and vascular dysfunction

BA Bakrania, FT Spradley… - Comprehensive …, 2020 - pmc.ncbi.nlm.nih.gov
Preeclampsia (PE), a hypertensive disorder, occurs in 3% to 8% of pregnancies in the
United States and affects over 200,000 women and newborns per year. The United States …

Preeclampsia history and postpartum risk of cerebrovascular disease and cognitive impairment: Potential mechanisms

AG Beckett, MD McFadden, JP Warrington - Frontiers in Physiology, 2023 - frontiersin.org
Hypertensive disorders of pregnancy such as preeclampsia, eclampsia, superimposed
preeclampsia, and gestational hypertension are major causes of fetal and maternal …

Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum

HE Collins, BT Alexander, AS Care… - American Journal …, 2024 - journals.physiology.org
Maternal mortality rates are at an all-time high across the world and are set to increase in
subsequent years. Cardiovascular disease is the leading cause of death during pregnancy …