Mucosal surfaces are lined by epithelial cells, which provide a complex and adaptive
module that ensures first-line defense against external toxics, irritants, antigens, and …

Introduction: Chronic obstructive pulmonary disease (COPD) is primarily an airway
condition, which mainly affects cigarette smokers and presents with shortness of breath that …

Curcumin is derived from the spice tumeric and has antiinflammatory and antineoplastic
effects in vitro and in animal models, including preventing aberrant crypt foci (ACF) and …

Introduction Cigarette smoke is a profound pro-inflammatory stimulus that contributes to
acute lung injuries and to chronic lung disease including COPD (emphysema and chronic …

COPD is a chronic airway inflammatory disease characterized mainly by neutrophil airway
infiltrations. Interleukin (IL)-1β and IL-17 are the key mediators of neutrophilic airway …

The purpose of this study is to evaluate the therapeutic effects of curcumin on airway
inflammation using LPS and cigarette smoke (LC)-induced COPD murine models and LPS …

Rationale: Most airway diseases, including chronic obstructive pulmonary disease (COPD),
are associated with excessive coughing. The extent to which this may be a consequence of …

Netrin-1 regulates inflammation but the mechanism by which this occurs is unknown. Here
we explore the role of netrin-1 in regulating the production of the prostanoid metabolite …

Clinical studies have indicated the co-occurrence of chronic obstructive pulmonary disease
(COPD) and psychiatric disorders, for example, comorbid depression. However, the …

The incidence of chronic obstructive pulmonary disease (COPD) has substantially increased
in recent decade. Cigarette smoke (CS) is the most important risk factor in the development …