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[HTML][HTML] Guidelines for clinical translation and commercialization of extracellular vesicles and exosomes based therapeutics
Extracellular vesicles (EVs) are lipid-bilayer delimited membrane structures released by
cells, and play a role in intercell communication and disease development. The Global …
cells, and play a role in intercell communication and disease development. The Global …
Ongoing clinical trials of nonviral siRNA therapeutics
Short interfering RNAs (siRNA) are a powerful class of genetic medicines whose clinical
translation can be hindered by their suboptimal delivery properties in vivo. Here, we provide …
translation can be hindered by their suboptimal delivery properties in vivo. Here, we provide …
Current status and outlook of advances in exosome isolation
W Liu, Z Ma, X Kang - Analytical and Bioanalytical Chemistry, 2022 - Springer
Exosomes are extracellular vesicles with a diameter ranging from 30 to 150 nm, which are
an important medium for intercellular communication and are closely related to the …
an important medium for intercellular communication and are closely related to the …
Biogenesis, composition and potential therapeutic applications of mesenchymal stem cells derived exosomes in various diseases
YG Yuan, JL Wang, YX Zhang, L Li… - International Journal …, 2023 - Taylor & Francis
Exosomes are nanovesicles with a wide range of chemical compositions used in many
different applications. Mesenchymal stem cell-derived exosomes (MSCs-EXOs) are …
different applications. Mesenchymal stem cell-derived exosomes (MSCs-EXOs) are …
Extracellular vesicle preparation and analysis: a state‐of‐the‐art review
In recent decades, research on Extracellular Vesicles (EVs) has gained prominence in the
life sciences due to their critical roles in both health and disease states, offering promising …
life sciences due to their critical roles in both health and disease states, offering promising …
Bioreducible exosomes encapsulating glycolysis inhibitors potentiate mitochondria-targeted sonodynamic cancer therapy via cancer-targeted drug release and …
Nanocarrier-assisted sonodynamic therapy (SDT) has shown great potential for the effective
and targeted treatment of deep-seated tumors by overcoming the critical limitations of …
and targeted treatment of deep-seated tumors by overcoming the critical limitations of …
[HTML][HTML] Extracellular vesicle-embedded materials
Extracellular vesicles (EVs) are small membrane-bound vesicles released by cells. EVs are
emerging as a promising class of therapeutic entity that could be adapted in formulation due …
emerging as a promising class of therapeutic entity that could be adapted in formulation due …
Exosomes: a promising avenue for cancer diagnosis beyond treatment
Z Wang, Q Wang, F Qin, J Chen - Frontiers in Cell and …, 2024 - frontiersin.org
Exosomes, extracellular vesicles secreted by cells, have garnered significant attention in
recent years for their remarkable therapeutic potential. These nanoscale carriers can be …
recent years for their remarkable therapeutic potential. These nanoscale carriers can be …
Global trends of exosomes application in clinical trials: a sco** review
Background Exosomes, nano-sized extracellular vesicles, have emerged as a promising
tool for the diagnosis and treatment of various intractable diseases, including chronic …
tool for the diagnosis and treatment of various intractable diseases, including chronic …
Broccoli-derived exosome-like nanoparticles alleviate loperamide-induced constipation, in correlation with regulation on gut microbiota and tryptophan metabolism
T Duan, X Wang, X Dong, C Wang… - Journal of Agricultural …, 2023 - ACS Publications
Constipation, a common gastrointestinal dysfunction, damages patients' life quality and
predisposes them to other serious diseases. Current strategies against constipation often …
predisposes them to other serious diseases. Current strategies against constipation often …