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The Role of the Microbiome in Pediatric Respiratory Diseases
The communities of bacteria and other microorganisms living in and on the human body—
which constitute the microbiome—have been studied for more than a century, but research …
which constitute the microbiome—have been studied for more than a century, but research …
Unique microbial landscape in the human oropharynx during different types of acute respiratory tract infections
H Li, X Wu, H Zeng, B Chang, Y Cui, J Zhang, R Wang… - Microbiome, 2023 - Springer
Background Secondary bacterial infections and pneumonia are major mortality causes of
respiratory viruses, and the disruption of the upper respiratory tract (URT) microbiota is a …
respiratory viruses, and the disruption of the upper respiratory tract (URT) microbiota is a …
Microbiome modifications by steroids during viral exacerbation of asthma and in healthy mice
K Yagi, AD Ethridge, NR Falkowski… - … of Physiology-Lung …, 2024 - journals.physiology.org
In the present studies, the assessment of how viral exacerbation of asthmatic responses with
and without pulmonary steroid treatment alters the microbiome in conjunction with immune …
and without pulmonary steroid treatment alters the microbiome in conjunction with immune …
The develo** immune system in preterm born infants: From contributor to potential solution for respiratory tract infections and wheezing
IC van Duuren, ORJ van Hengel, J Penders, L Duijts… - Allergy, 2024 - Wiley Online Library
Moderate‐late preterm‐born infants experience more frequent and severe respiratory tract
infections and wheezing compared to term‐born infants. Decreasing the risk on respiratory …
infections and wheezing compared to term‐born infants. Decreasing the risk on respiratory …
Proteomics endoty** of infants with severe bronchiolitis and risk of childhood asthma
Background Bronchiolitis is the leading cause of hospitalization in US infants and a major
risk factor for childhood asthma. Growing evidence supports clinical heterogeneity within …
risk factor for childhood asthma. Growing evidence supports clinical heterogeneity within …
Exclusive breast-feeding, the early-life microbiome and immune response, and common childhood respiratory illnesses
Background The impact of breast-feeding on certain childhood respiratory illnesses remains
controversial. Objective We sought to examine the effect of exclusive breast-feeding on the …
controversial. Objective We sought to examine the effect of exclusive breast-feeding on the …
Can therapeutic targeting of the human microbiome influence asthma management? A pro/con debate
AL Kau, AL Rosen, C Rosas-Salazar - The Journal of Allergy and Clinical …, 2024 - Elsevier
Asthma is a clinically heterogeneous disease, and despite substantial improvements in
therapies, there remains an unmet need for well-tolerated, effective treatments …
therapies, there remains an unmet need for well-tolerated, effective treatments …
Viral genetic determinants of prolonged respiratory syncytial virus infection among infants in a healthy term birth cohort
Background Respiratory syncytial virus (RSV) is associated with acute respiratory infection.
We sought to identify RSV variants associated with prolonged infection. Methods Among …
We sought to identify RSV variants associated with prolonged infection. Methods Among …
Upper respiratory tract microbiota dynamics following COVID-19 in adults
To date, little is known about the effect of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), the virus responsible for the coronavirus disease 2019 (COVID-19) …
(SARS-CoV-2), the virus responsible for the coronavirus disease 2019 (COVID-19) …
New paradigms in acute viral bronchiolitis: Is it time to change our approach?
Viral bronchiolitis is the most common pediatric acute respiratory infection leading to
hospitalization, and it causes significant healthcare burden worldwide. Current guidelines …
hospitalization, and it causes significant healthcare burden worldwide. Current guidelines …