Motor symptoms and schizophrenia

S Walther, W Strik - Neuropsychobiology, 2012 - karger.com
Classical schizophrenia literature reports motor symptoms as characteristic of the disorder.
After the introduction of neuroleptic drugs, the existence of genuine motor disorders was …

The error-related negativity (ERN) and psychopathology: Toward an endophenotype

DM Olvet, G Hajcak - Clinical psychology review, 2008 - Elsevier
The ERN is a negative deflection in the event-related potential that peaks approximately 50
ms after the commission of an error. The ERN is thought to reflect early error-processing …

[HTML][HTML] Negative symptoms of schizophrenia: clinical characteristics, pathophysiological substrates, experimental models and prospects for improved treatment

MJ Millan, K Fone, T Steckler, WP Horan - European …, 2014 - Elsevier
Schizophrenia is a complex and multifactorial disorder generally diagnosed in young adults
at the time of the first psychotic episode of delusions and hallucinations. These positive …

Categorical and dimensional approaches to negative symptoms of schizophrenia: focus on long-term stability and functional outcome

S Galderisi, P Bucci, A Mucci, B Kirkpatrick, S Pini… - Schizophrenia …, 2013 - Elsevier
Negative symptoms of schizophrenia represent a heterogeneous psychopathological
domain. Both categorical and dimensional approaches have been proposed to reduce …

Primary and persistent negative symptoms: concepts, assessments and neurobiological bases

A Mucci, E Merlotti, A Üçok, A Aleman… - Schizophrenia research, 2017 - Elsevier
Primary and persistent negative symptoms (PPNS) represent an unmet need in the care of
people with schizophrenia. They have an unfavourable impact on real-life functioning and …

[HTML][HTML] Deficit schizophrenia: an update

B Kirkpatrick, S Galderisi - World Psychiatry, 2008 - ncbi.nlm.nih.gov
The criteria for deficit schizophrenia were designed to define a group of patients with
enduring, primary (or idiopathic) negative symptoms. In 2001, a review of the literature …

Neuroimaging evidence for the deficit subtype of schizophrenia

AN Voineskos, G Foussias, J Lerch, D Felsky… - JAMA …, 2013 - jamanetwork.com
Importance A major obstacle to the identification of the neurobiological correlates of
schizophrenia is the substantial clinical heterogeneity present in this disorder. Dividing …

Pharmacological treatment of negative symptoms in schizophrenia: update and proposal of a clinical algorithm

G Cerveri, C Gesi, C Mencacci - Neuropsychiatric Disease and …, 2019 - Taylor & Francis
The clinical presentation of schizophrenia encompasses symptoms divided into three
dimensions: positive, negative, and cognitive. Negative symptoms (NS), in particular, have a …

Neurobiological background of negative symptoms

S Galderisi, E Merlotti, A Mucci - European archives of psychiatry and …, 2015 - Springer
Studies investigating neurobiological bases of negative symptoms of schizophrenia failed to
provide consistent findings, possibly due to the heterogeneity of this psychopathological …

Multivariate associations among behavioral, clinical, and multimodal imaging phenotypes in patients with psychosis

DA Moser, GE Doucet, WH Lee, A Rasgon… - JAMA …, 2018 - jamanetwork.com
Importance Alterations in multiple neuroimaging phenotypes have been reported in
psychotic disorders. However, neuroimaging measures can be influenced by factors that are …