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A Mini-Review on the Common Antiviral Drug Targets of Coronavirus
J Wang, Q Zhu, X **ng, D Sun - Microorganisms, 2024 - mdpi.com
Coronaviruses in general are a zoonotic pathogen with significant cross-species
transmission. They are widely distributed in nature and have recently become a major threat …
transmission. They are widely distributed in nature and have recently become a major threat …
Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation
E Olmedillas, RR Rajamanickam, RD Avalos… - …, 2023 - pmc.ncbi.nlm.nih.gov
The 800 million human infections with SARS-CoV-2 and the likely emergence of new
variants and additional coronaviruses necessitate a better understanding of the essential …
variants and additional coronaviruses necessitate a better understanding of the essential …
Revealing the Potential of a Chimaera: a Peptide‐Peptide Nucleic Acid Molecule Designed To Interact with the SARS‐CoV‐2 Nucleocapsid Protein
Numerous RNA‐binding proteins have modular structures with folded domains and
intrinsically disordered regions, making their atomic characterization difficult. This severely …
intrinsically disordered regions, making their atomic characterization difficult. This severely …
High-resolution melting analysis for detection of nucleotide mutation markers in the polymerase-acidic (PA) gene of influenza virus that are associated with baloxavir …
The I38T substitution in the influenza virus polymerase-acidic (PA) subunit is a resistance
marker of concern for treatment with the antiviral baloxavir marboxil (BXM). Thus, monitoring …
marker of concern for treatment with the antiviral baloxavir marboxil (BXM). Thus, monitoring …
[PDF][PDF] DiMA: sequence diversity dynamics analyser for viruses
Sequence diversity is one of the major challenges in the design of diagnostic, prophylactic,
and therapeutic interventions against viruses. DiMA is a novel tool that is big data-ready and …
and therapeutic interventions against viruses. DiMA is a novel tool that is big data-ready and …
Glycyrrhetinic acid prohibiting fusion peptides from fusing with cell membrane
Z Jia, R Wu, Y Hao, X Song, S Hou, C Shi, Y Cui… - ChemNanoMat - Wiley Online Library
The inhibition of the fusion peptide (FP) of the spike protein of coronaviruses, which
mediates interactions with the host cell membrane, plays a critical role in the membrane …
mediates interactions with the host cell membrane, plays a critical role in the membrane …