The discovery of genetic variation and the assembly of genome sequences are both
inextricably linked to advances in DNA-sequencing technology. Short-read massively …

Metagenomics is a segment of conventional microbial genomics dedicated to the
sequencing and analysis of combined genomic DNA of entire environmental samples. The …

Carbapenem-resistant Acinetobacter baumannii (CRAB) has emerged as a major global
pathogen with limited treatment options. No new antibiotic chemical class with activity …

Abstract SPAdes—St. Petersburg genome Assembler—was originally developed for de
novo assembly of genome sequencing data produced for cultivated microbial isolates and …

Microbiota-derived metabolites that elicit DNA damage can contribute to colorectal cancer
(CRC). However, the full spectrum of genotoxic chemicals produced by indigenous gut …

The 16S rRNA gene has been a mainstay of sequence-based bacterial analysis for
decades. However, high-throughput sequencing of the full gene has only recently become a …

The cyclic oligonucleotide-based antiphage signalling system (CBASS) and the pyrimidine
cyclase system for antiphage resistance (Pycsar) are antiphage defence systems in diverse …

Background The possibility of generating large RNA-sequencing datasets has led to
development of various reference-based and de novo transcriptome assemblers with their …

The human gut microbiota produces dozens of metabolites that accumulate in the
bloodstream,, where they can have systemic effects on the host. Although these small …

Accumulating evidence indicates that gut microorganisms have a pathogenic role in
autoimmune diseases, including in multiple sclerosis. Studies of experimental autoimmune …